forces across membranes 1 Flashcards
(8 cards)
what can move freely between the ISF,ICF and plasma and what cannot?
gases move freely
nutrients and waste products move freely through carrier proteins.
ions do not move freely.
8 features of membranes
1- selective barrier
2-flexible: due to presence of fatty acids which allow cells to shrink and swell
3: act as recognition site for molecules: receptors on surface bond to specific molecules due to complementary shape. this triggers a chemical reaction within the cell
4-act as a very good insulator: phospholipid bilayer allows electrical charge to be maintained within the cell
5- made up of a thin, bilayer of phospholipids
6- proteins embedded in structure
7-constantly being metabolised and adjusted according to the needs of the cell.
8-permeability may vary.
different functions of proteins within the cell?
INTEGRAL PROTEINS: span the whole cell membrane. Same rotation as phospholipids. Amphipathic. If they are removed they alter the function of the membrane.
1- enzymes: catalyse reactions of cell-surface membranes.
2- receptor
3-transporter: channel and carrier
PERIPHERAL PROTEINS: Do not span the whole membrane. Are not amphipathic. If removed will not alter the function of the membrane
how do the receptor proteins work?
they have a shape complementary to certain molecules.
if these molecules bind they lead to a chemical change within the cell.
the molecules they bind to are known as ligands ( neurotransmitters or hormones)
antagonists are molecules which have the same shape as ligands and can block the receptor site
different type of protein transporters?
channel: form a continuous pore between the ECF and the ICF. water can always flow between them.
carrier: opens to ICF first and then ECF.
function of peripheral-membrane proteins?
1-attach cell to extracellular matrix
2-bind cell to intracellular cytoskeleton
3-control cell interaction with other cells.
different composition of cell- membranes
myelin: good insulator-has low protein content and high lipid content
plasma membranes; 50/50
energy transduction proteins: 75% protein due to many mitochondria
different composition of lipid bilayer
may have lipids(glycolipids) or proteins(glycoproteins) attached to them EXTRACELLULARLY.
important in self-cell recognition.