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Toxicology Final > Forensic Aspects of Drug Abuse 3 > Flashcards

Forensic Aspects of Drug Abuse 3 Flashcards

(52 cards)

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1
Q

What is PCP?

A
  • dissociative anaesthetic with hallucinogenic properties
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2
Q

What was PSP first developed as?

A

IV anesthetic for humans

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3
Q

What are the street names for PCP?

A
  • magic dust
  • angel dust
  • embalming fluid
  • elephant tranquilizer
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4
Q

What the most common method of ingestion of PCP?

A
  • smoked
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5
Q

How to they formulate the PCP to enable it to be smoked?

A
  • applied in either powder or liquid form to a variety of leafy substances which can then be smoked in a pipe or homemade
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6
Q

What are the desired effects of PCP?

A
  • intense euphoria
  • hallucinations
  • relaxation
  • dissociation form the environment
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7
Q

What is the onset of effect from PCP?

A

1-5 minutes if smoked

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8
Q

What is the duration of PCP effect?

A

4-6 hours or longer

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9
Q

What are the physical effects of PCP?

A
  • agitation, confusion
  • disorientation
  • increased pain threshold
  • elevated body temp
  • moon walking
  • cyclic behaviour
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10
Q

What are the s/s of PCP toxicity?

A
  • delirium
  • hallucinations
  • convulsions
  • violent reactions
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11
Q

What happens with overdose associated with PCP?

A
  • deep coma
  • seizures
  • death is due to respiratory arrest and potentially cardiac arrest
    (longterm use- can lead to psychosis)
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12
Q

Does PCP cause both physiological and psychological dependance?

A
  • psych: YES

- physiological: NO

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13
Q

What kind of drug is GHB classified as?

A

a CNS depressant

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14
Q

What was GHB used for in the past?

A
  • combo with anaesthetic
  • experimental tx for narcolepsy
  • alcohol withdrawal
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15
Q

What are the street names for GHB?

A
  • easy lay
  • liquid E
  • G
  • salt water
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16
Q

What are the desired effects from GHB?

A
  • relaxation
  • sense of well being
  • loss of social inhibitions
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17
Q

What is the onset of GHB?

A
  • 5-20 minutes
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18
Q

What is the duration of action of GHB?

A

2-3 hours (makes it difficult because cannot be detected in blood after around 6 hours - implications for date rape trials)

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19
Q

What are the other effects associated with GHB?

A
  • amnesia
  • drowsiness
  • impaired judgement
  • slowed rxn time
  • slurred speech
  • loss of balance
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20
Q

At a higher dose, what are the physical reactions to GHB?

A
  • LOC
  • slowed HR
  • seizures
  • decreased resp
  • coma
  • death
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21
Q

GHB is an ________________

Study These Flashcards
A

endogenous metabolite

22
Q

GHB may be a product of _______ metabolism

23
Q

What are the properties of cannabis?

Study These Flashcards
A
  • CNS depressant, stimulant and has hallucinogenic properties as well
24
Q

What are the useful properties of cannabis used medicinally?

Study These Flashcards
A
  • antiemetic
  • management of glaucoma
  • antispasmodic
  • appetite enhancer
25
Dronabinol is a synthetic _____________
trans (-) isomer of THC
26
What is dronabinol approved for?
- n/v associated with cancer | - anorexia and weight loss with AIDs
27
What is nabilone?
- synthetic chromenone derivative of THC
28
What is nabilone approved for?
- n/v associated with cancer | - anorexia and weight loss with AIDs
29
Sativex is a ______ and _______
natural THC and cannabidiol
30
Sativex is approved for what?
tx of neuropathic pain and spasticity associated with MS
31
What are the street names associated with cannabis?
``` dope ganja grass J mary jane ```
32
What is the best part of the weed plant?
resin at the top of the plant has THC that is the best
33
What is the desired effects of cannabis?
- euphoria - general sense of well being - relaxation - loss of inhibition
34
What is the duration of a high from cannabis(smoked)
2-3 hours
35
What are the other effects of cannabis? (more physical)
- distortion of time, space, body image - impairment of recent memory and concentration - mild confusion; disorientation - reduced attention span - reduced ability to process information - difficulty with balance - dry mouth
36
What are the s/s of cannabis toxicity?
- fearfulness - anxiety - mild paranoia
37
What is heroin classified as?
- CNS depressant
38
Heroin is _______ times more potent than morphine
2-3 x
39
How is morphine produced?
- by treating morphine with acetic anhydride
40
What are some of the street names associated with heroin?
- antifreeze - big H - brown sugar
41
What are the methods of heroin ingestion?
- injection - smoking - snorting
42
What is the point of using a depressant (heroin) at the same time as using a stimulant (crack rocks)
- crack rocks have an effect right away (lasts around 20 minutes) - by the time the crack rocks wear off, then the heroin starts to work
43
What are the desired effects associated with heroin?
- euphoria - sense of well being - relief of pain
44
What is the onset of heroin action?
- immediate euphoria | - 15-30 minutes for the other physical effects
45
What is the duration of the physical effects associated with heroin?
3-6 hours for the physical effects
46
What is the "on the nod" | effect associated with heroin?
- semiconscious - droopy eyelids - head slumped forward, chin on chest - easily awakened - altert to questions
47
What narcotic will not cause constricted pupils?
- demerol
48
What are the other physical effects associated with heroin?
- slowed reflexed - slow, raspy speech - facial itching - nausea - difficulty with urination - slow, deliberate movement
49
What is associated with toxicity of heroin?
- resp depression - coma - death
50
Does heroin cause both psychological and physiological dependence?
- YES
51
What are the s/s associated with withdrawal?
- insomnia, vomiting, diarrhea, hot and cold flashes, weakness and cold like symptoms
52
What is one of the main interpretation challenges around heroin use?
- heroin is not detected in the body fluids and requires a special extraction procedure(requires extraction at a pH of 8)

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