Formulations

Question 1

Transdermal Administration

• matrix transdermal patch
• Ex: Rotigotine (Neupro ®) (PD)

Answer 1

1. Application of the patch once a day, same time daily
2. patch is 24hrs
   - change next day at diff site
   - abdomen, thigh, hip, shoulder, arm

• slow release / long lasting
• avoids hepatic first pass metabolism
• can be removed quickly in case of s/e