Foundational Concept 7A Flashcards

Needed: Biological Bases of Behavior, Personality, Motivation, Attitudes Done: Psychological Disorders

1
Q

MCAT Behavioural Sciences - Psychological Disorders

Which of the following is an example of a negative symptom seen in schizophrenia?

  1. (Auditory) Hallucinations
  2. Disorganised Behavior
  3. Disturbance of Affect
  4. Delusions

Why is this a negative symptom?

Challenge: list and define the positive (4) and negative (2) symptoms

A
  1. Disturbance of Affect

Negative symptoms are the absence of normal/desired behavior

Positive Symptoms:
Delusions (false beliefs discordant with reality)
Hallucinations (perceptions that are not due to external stimuli)
Disorganised thought (loosening of associations), Disorganised behavior (inability to carry out activities of daily living)

Negative Symptoms:
Disturbance of affect (expression of emotions)
Avolition (decreased engagement in purposeful, goal-directed actions)

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2
Q

MCAT Behavioural Sciences - Psychological Disorders

During an interview with a schizophrenic patient, a psychiatrist keeps repeated what the psychiatrist says. This phenomenon is known as:
1. Echolalia
2. Ecopraxia
3. Loosening of Associations
4. Neologisms

Why?

Challenge: define each phenomenon

A
  1. Echolalia

Echolalia (repeating another’s words)
Echopraxia (imitating another’s actions)
Loosening of Associations (disorganised thought) Neologisms (speech has no structure or involve invented words)

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3
Q

MCAT Behavioural Sciences - Psychological Disorders

A 42-year-old woman has always been extremely neat and tidy. She works as a secretary and stays long after normal working hours to check the punctuation and spelling of the letters she prepared during the day. Her boss referred her for counseling after she repeatedly got into fights with her coworkers. “They don’t take the job to heart,” she says. “They just joke around all the day”. The most likely preliminary diagnosis for this patient is:
1. Obsessive-compulsive personality disorder
2. Antisocial personality disorder
3. Narcissistic personality disorder
4. Borderline personality disorder

Why?

Challenge: define each PD and its cluster

A
  1. Obsessive-Compulsive Personality Disorder
    Focusing on details, loving routine, having a sense that there is only one right way to do things, and a lack of humor

Obsessive-compulsive personality disorder (Cluster C)
Antisocial personality disorder (Cluster B)
-> Pattern of disregard for and violations of the rights or others
Narcissistic personality disorder (Cluster B)
-> Grandiose sense of self-importance or uniqueness
Borderline personality disorder (Cluster B)
-> Pervasive instability in interpersonal behavior, mood, or self-image

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4
Q

MCAT Behavioural Sciences - Psychological Disorders

Which of the following is true with regard to a major depressive episode?
1. It may less than two weeks
2. It must involve thoughts of suicide or a suicide attempt
3. It may involve a decrease in sleep
4. It must involve feelings of sadness

Why?

Challenge: list all the symptoms of a major depressive episode and criteria for diagnosis

A

3.It may involve a decrease in sleep

Sleep disturbance is one of the nine cardinal symptoms

At least two weeks with at least five of the following symptoms:
SIG E. CAPS - > Sadness + S(sleep) + I(interest) + G(guilt) + E(energy) + C(concentration) + A(appetite) + P(psychomotor symptoms) + S(suicidal thoughts)

Symptoms must cause significant distress or impairment in functioning

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5
Q

MCAT Behavioural Sciences - Psychological Disorders

A 36-year-old who works from home is referred for evaluation. He is reluctant to venture out to meet with other people and rarely has people in to visit. When selected for a company-wide award, he refused to have his picture taken for the company newsletter. During an assessment, he averts his face and asks the examiner to “stop looking at me”. Although he is average in appearance, he is convinced that his face is ugly and misshapen. The most likely diagnosis for this man would be:
1. Schizophrenia
2. Obsessive-compulsive disorder
3. Body dismorphic disorder
4. Schizoid personality disorder

Why?

A
  1. Body dysmorphic disorder

Central issue is the negative appraisal of his own appearance

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6
Q

MCAT Behavioural Sciences - Psychological Disorders

A young woman of unknown age is brought by Philadelphia police into the local ED for evaluation after they found her wandering in the park. She carries no purse or identification. She is unable to state her name or any details about her life, except that the name phoenix seems familiar. The police in Arizona are contacted and find a missing persons report matching the patient’s description. Based on this information, the most likely diagnosis for this patient is:
1. Depersonalisation/Derealisation Disorder
2. Dissoaciative Identity Disorder
3. Somatic Symptom Disorder
4. Dissociative amnesia with dissociative fugue

Why?

Challenge: what are the main features of each?

A

4.Dissociative Amnesia with Dissociative Fugue

Dissociative fugue is characterised by suddent travel or change in normal day-to-day activites, and occurs in some cases of dissociative amnesia. Symptoms include an inability to recall one’s past or confision about one’s identity.

  1. Depersonalised (feels detatched from their own mind or body)/Derealisation (from their surroundings) Disorder
  2. Dissociative Identity Disorder - two(+) personalities that recurrently take control of a person’s behaviour
  3. Somatic Symptom Disorder - at least one somatic symptom that is accompanied by disproportionate concerns about its seriousness, devotion of excessive amount of time and energy to it, or elevated levels of anxiety
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7
Q

MCAT Behavioural Sciences - Psychological Disorders

In addition to being a freestanding diagnosis, argoraphobia is most often seen in association with which other psychiatric diagnosis?
1. Obsessive-compulsive disorder
2. Avoidant personality disorder
3. Generalised anxiety disorder
4. Panic disorder
Why is it seen in association?

Challenge: what are the main features of each disorder?

A

4.Panic disorder

Agoraphobia, a fear of places/situations in which it would be difficult to escape, is commonly seen in panic disorder. Concerns about having a panic attack in public may make these individuals fearful of leaving their home

  1. Obsessive-Compulsive Disorder: obsessions (persistent, intrusive thoughts and impulses), which produce tension, and compulsions (repetitive tasks) that relieve the tension
  2. Avoidant Personality Disorder: extreme shyness and fear of rejection, intense desire for social affection and acceptance
  3. Generalised Anxiety Disorder: disproportionate and persistent worry about many different things
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8
Q

MCAT Behavioural Sciences - Psychological Disorders

A 28-year-old male comes to a clinic concerned that he has pancreatic cancer. Review of his medical records show that this is the fourth time in the past year that the patient has appeared for medical attention. No identifible medical problem is found. When confronted with this history, he confesses that he feels relieved after being told all of the tests are negative, but soon becomes worried again that he has cancer. Based on this information, the most likely diagnosis for the patient would be:
1. Major depressive disorder
2. Illness anxiety disorder
3. Conversion disorder
4. Narcisstic personality disorder

Challenge: define each listed disorder

A

2.Illness Anxiety Disorder

  1. major depressive disorder: mood disorder characterised by at least one major depressive episode
  2. illness anxiety disorder: consumed with thoughts about having/developing a serious medical condition
  3. conversion disorder: unexplained symptoms that affect voluntary motor or sensory functions
  4. narcisstic personality disorder: grandoise sense of self-importance or uniqueness
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9
Q

MCAT Behavioural Sciences - Psychological Disorders

A physician is attempting to diagnose a patient’s mental disorder based on a set of symptoms. The confirmed symptoms currently include appetite disturbance, substantial weight change, decreased energy, a feeling of worthlessness, and excessive guilt.

What two disorders could these symptoms indicate?
1. Major depressive disorder and bipolar disorders
2. Dissociative amnesia and depersonalisation/derealisation disorder
3. Alzheimer’s disease and Parkinson’s disease
4. Specific phobia and panic disorder

What should a physician ask about to distinguish between the two possible disorders?
1. Whether the patient has amnesia
2. Whether the patient has also had manic episodes
3. Whether the patient is irrationally afraid of anything
4. Whether the patient has experienced difficulty performing familiar tasks

Why?

A

1.Major depressive disorder and bipolar disorders
2.Whether the patient has also had manic episodes

Both have depressive episodes, bipolar also has manic episodes

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10
Q

MCAT Behavioural Sciences - Psychological Disorders

A mother notices that her teenage son seems to have a phobia for snakes. In the past week, on several occasions, the teenager has had more severe symptoms than usual, without seeing or thinking about a snake. Which disorder could cause this reaction?
1. Schizophrenia
2. Antisocial personality disorder
3. Obsessive-compulsive disorder
4. Panic disorder

Challenge: define each disorder

A

4.Panic disorder
Signs of panic and irrational fear without any instigating object present indicates panic disorder.

  1. Schizophrenia: a breakdown in the relation between thought, emotion, and behavior
  2. Antisocial personality disorder: pattern of disregard for and violations of the rights of others
  3. Obsessive-compulsive disorder: characterised by obsessions, which produce tension, and compulsions that relieve the tension but significantly impair a person’s life
  4. Panic disorder: repeated panic attacks
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11
Q

MCAT Behavioural Sciences - Psychological Disorders

Splitting is a defense mechanism typically seen with which personality disorder?
1. Antisocial personality disorder
2. Borderline personality disorder
3. Histrionic personality disorder
4. Narcissistic personality disorder

What is splitting?

Challenge: define each disorder

A

2.Borderline personality disorder

Consideration of others as “all good” or “all bad”

  1. Antisocial personality disorder: pattern of disregard for and violations of the rights of others
  2. Borderline personality disorder: pervasive instability in interpersonal behaviour, mood, or self-image
  3. Histrionic personality disorder: constant attention-seeking behaviour
  4. Narcissistic personality disorder: grandoise sense of self-importance or uniqueness
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12
Q

MCAT Behavioural Sciences - Psychological Disorders

A woman comes to the doctor with a two-week history of complete paralysis of her left arm. She has no injury to the extremity, and full neurological workup fails to demonstrate any underlying cause. She seems surprisingly unconcerned about the paralysis, and seems more worried about an argument she had one month ago in which she hit her daughter. Based on this information, the woman’s most likely diagosis is:
1. Conversion disorder
2. Generalised anxiety disorder
3. Ilness anxiety disorder
4. Histironic personality disorder

Why?

Challenge: define each disorder

A

1.Conversion disorder (w/ la belle indifférence)

  1. Conversion disorder: unexplained symptoms affeted voluntary motor or sensory symptoms
  2. Generalised anxiety disorder: disproportionate and persistent worry about many different things
  3. Ilness anxiety disorder: consumed with thoughts about having/developing a medical condition
  4. Histironic personality disorder: constant attention-seeking behaviour
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13
Q

MCAT Behavioural Sciences - Psychological Disorders

A woman notices her father has started to move his fingers in such a way that it looks like he is rolling something, despite nothing actually being there. She also notes slowed movement and a shuffling gait. Which neurotransmitter is likely to be present in decreased levels in her father’s brain?
1. Epinephrine
2. Histamine
3. Dopamine
4. Serotonin

A

3.Dopamine
Likely has Parkinson’s disease, which is caused by decreased dopamine production in the substantia nigra

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14
Q

MCAT Behavioural Sciences - Psychological Disorders

Which of the following is/are true regarding bipolar disorders?
A. They have little, if any, genetic heritability
B. They are associated with increased levels of serotonin in the brain
C. They all require at least one depressive episode for diagnosis

  1. A only
  2. B only
  3. A and C only
  4. B and C only

Why?

A
  1. They are associated with increased levels of serotonin in the brain

They are highly heritable and are associated with increased levels of norepinephrine and serotonin in the brain.

Bipolar I doesn’t require a major depressive episode (only a manic episode). Bipolar II requires at least one hypomanic episode and one major depressive episode. Cyclothymic disorder has at least one hypomanic episode an dysthymia (milder, but long-lasting form of depression)

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15
Q

MCAT Behavioural Sciences - Psychological Disorders

List and define each Cluster A personality disorder (3)

A
  1. Paranoid: pervasive distrust of others
  2. Schizotypal: pattern of odd or eccentric thinking
  3. Schizoid: pervasive pattern of detachment from social relationships and a restricted range of emotional expression
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16
Q

MCAT Behavioural Sciences - Psychological Disorders

List and define each Cluster B personality disorder (4)

A
  1. Antisocial: pattern of disregard for and violations of the rights of others
  2. Borderline: pervasive instability in interpersonal behaviour, mood, and self-image
  3. Histrionic: constant attention-seeking behaviour
  4. Narcisstic: grandoise sense of self-importance or uniqueness
17
Q

MCAT Behavioural Sciences - Psychological Disorders

List and define each Cluster C personality disorder (3)

A
  1. Avoidant: extreme shyness and fear of rejection
  2. Dependent: continuous need for reassurance
  3. Obsessive-Compulsive: perfectionistic and inflexible, tending to like rules and order
18
Q

MCAT Behavioural Sciences - Psychological Disorders

Define a delusion and the five common examples

A

Delusion: false beliefs discordant with reality
1. Reference: common elements in the environment are directed toward the individual
2. Persecution: person is being deliberately interfered with, discriminated against, plotted against, or threatened
3. Grandeur: person is remarkable in some significant way
4. Thought Broadcasting: thoughts are broadcast to the external world
5. Thought Insertion: thoughts are being placed in their head

19
Q

MCAT Behavioural Sciences - Psychological Disorders

What are five common anxiety disorders and how can they be identified?

A
  1. Generalised Anxiety Disorder: persistent worry and tension
  2. Panic Disorder: repeated panic attacks
  3. Social Anxiety Disorder: fear and avoidance of social situations
  4. Obsessive Compulsive Disorder: intrusive thoughts and repetitive behaviours
  5. Agoraphobia: fear of being in places of situations where it might be hard for an individual to escape
20
Q

MCAT Behavioural Sciences - Psychological Disorders

What are the four types of symptoms associated with PTSD?

What is the difference between PTSD and acute stress disorder?

Challenge: give examples of each type

A

Intrusive (recurrent reliving of the event)
Avoidance (deliberate attempts to avoid the memories)
Negative Cognitive (inability to recall key features of the event, negative mood/emotions, feeling distanced from others, persistent negative view of thr world)
Arousal (increased startle response, irritability, anxiety, reckless behaviour, sleep disturbances)

PTSD requires symptoms to last more than a month.

21
Q

MCAT Behavioural Sciences - Psychological Disorders

What are three common somatic symptom disorders and how can they be identified?

A

Somatic Symptom Disorder: at least one somatic symptom that is accompanied by disproportionate concerns about its seriousness
Illness Anxiety Disorder: consumed thoughts about having/developing a serious medical condition
Conversion Disorder: unexplained symptoms affected by voluntary motor or sensory symptoms

22
Q

MCAT Behavioural Sciences - Psychological Disorders

How do you differentiate between bipolar I, bipolar II, and cyclothymic disorder?

A

Bipolar I - manic episodes with or without major depressive episodes
Bipolar II - hypomania with at least one major depressive episode
Cyclothymic - combination of hypomanic episodes and periods of dysthymia

23
Q

MCAT Behavioural Sciences - Psychological Disorders

What are three depressive disorders and their identifiers?

A
  1. Major Depressive Disorder: mood disorder characterised by one major depressive episode (SIG E. CAPS)
  2. Persistent Depressive Disorder: dythymia most of the time for at least two years
  3. Seasonal Affective Disorder: best characterised as MDD with seasonal onset (not freestanding in the DSM-5)
24
Q

MCAT Behavioural Sciences - Psychological Disorders

What are the nine key symptoms of major depressive disorder?

A

SIG E. CAPS
(Sadness +) Sleep + Interest + Guilt + Energy + Concentration + Appetite + Psychomotor Symptoms + Suicidal Thoughts

25
Q

MCAT Behavioural Sciences - Psychological Disorders

What are three dissociative disorders and their identifiers?

Challenge: What is a dissociative fugue?

A

Dissociative Amnesia: inability to recall past experiences
Dissociative Identity Disorder: two or more personalities that take control of a person’s behaviour
Depersonalisation/Derealisation Disorder: feels detached from their own mind and body (depersonalisation) and their surroundings (derealisation)

26
Q

MCAT Behavioural Sciences - Psychological Disorders

What is the diagnostic criteria for schizophrenia?

A

Delusions, hallucinations, disorganised thought, disorganised behaviour, disturbance of affect, avolition

At least two of these symptoms for at least six months. One of which must be delusions, hallucinations, or disorganised speech.

27
Q

MCAT Behavioural Sciences - Psychological Disorders

What are the two approaches to understanding psychological disorders?

A

Biomedical -> any disorder has roots in biomedical disturbances so solution should also be of a biomedical nature
Biopsychosocial -> assumes there are biological, psychological, and social components

28
Q

MCAT Behavioural Sciences - Psychological Disorders

What are the definitions of concordance rate, point prevalence, and lifetime prevalence (in respect to psychological disorders)?

A

Concordance Rate: the probability that a person with a particular familial relationship to the patient has the same disorder as the patient
Point Prevalence: the percentage of people in a given population who have a given psychological disorder at any particular point in time
Lifetime Prevalence: the percentage of people in a certain population who will have been given a psychological disorder at any point in their lives

29
Q

MCAT Behavioural Sciences - Psychological Disorders

What are the biological bases of Parkinson’s and Alzheimer’s disease?

A

Parkinson’s: decreased dopamine production in the substantia nigra
Alzheimer’s: abnormal build-up of proteins (beta-amyloid and tau) in and around brain cells

30
Q

MCAT Behavioural Sciences - Psychological Disorders

What are the two proteins implicated in Alzheimer’s disease, and how do they form?

A
  1. Beta-amyloid: Forms plaques outside neurons.
  2. Tau: Forms tangles inside neurons.
31
Q

MCAT Behavioural Sciences - Psychological Disorders

What are the biological bases of depression and schizophrenia?

A

Depression - alterations in neurotransmitter levels, particularly serotonin, norepinephrine, and dopamine.
Schizophrenia - interplay of genetic, neurodevelopmental, and environmental factors. Excessive dopamine activity in certain brain regions

32
Q

MCAT Behavioural Sciences - Psychological Disorders

What structural changes are associated with depression, schizophrenia, Alzheimer’s disease, and Parkinson’s disease?

A

Depression: reduced volume of the hippocampus and prefrontal cortex, decreased myelination

Schizophrenia: enlarged ventricles, decreased gray matter volume in the frontal and temporal lobes, hippocampus and thalmus. Abnormalities in white matter tracts, including the corpus callosum

Alzheimer’s: formation of beta-amyloid plaques and neurofibrillary tangles. Progressive atrophy of the hippocampus and cortical regions involved in memory/cognition, and enlargment of the ventricles

Parkinson’s: degeneration of the dopamine-producing neurons in the substantia nigra, and atrophy of the basal ganglia.