French_CVPR_SNS _Drugs Flashcards
The CVPR Drugs and their respective receptor (23 cards)
What is the effect of Indirect adrenergic agonists?
•They will increase NE release
Isoproterenol acts on what receptor and how?
- Isoproterenol [β1-β2]
* Agonist
Albuterol acts on what receptor and how?
- Albuterol [β2]
* Agonist
Phenylephrine acts on what receptor and how?
- Phenylephrine [α1]
* Agonist
Pseudoephedrine acts on what receptor and how?
- Pseudoephedrine (i)
* Agonist
Dobutamine acts on what receptor and how?
- Dobutamine [β1]
* Agonist
Dopamine acts on what receptor and how?
- Dopamine [D1] + (i)
* Agonist
NE acts on what receptor and how?
- NE [α1-α2-β1]
* Agonist
Epinephrine acts on what receptor and how?
- Epinephrine [α1-α2-β1-β2]
* Agonist
Doxazosin-Terazosin-Prazosin act on what receptor and how?
- Doxazosin-Terazosin-Prazosin [α1]
* Antagonist
Metoprolol-Atenolol act on what receptor and how?
- Metoprolol-Atenolol [β1]
* Antagonist
Propranolol acts on what receptor and how?
- Propranolol [β1-β2]
* Antagonist
Labetalol-Carvedilol act on what receptor and how?
- Labetalol-Carvedilol [α1-β1-β2]
* Antagonist
Clonidine acts on what receptor and how?
- Clonidine [α2] agonist
* Ask yourself? why is this drug in the SNS antagonist column but acts on α2 as an agonist?
What drugs have α1 agonist activity?
Epinephrine, NE, Phenylephrine
What drugs have α2 agonist activity?
Epinephrine, NE and clonidine.
What drugs have β1 agonist activity?
Epinephrine, NE, Isoproterenol, Dobutamine
What drugs have β2 agonist activity?
Epinephrine, Isoproterenol, Albuterol
What drugs have D1 agonist activity?
Dopamine
What drugs have α1 Antagonist activity?
Doxazosin, Terazosin, Prazosin, Labetalol, Carvedilol
What drugs have α2 Antagonist activity?
None on French’s ANS table. Why?
What drugs have β1 Antagonist activity?
Metoprolol, Atenolol, Propranolol, Labetalol, Carvedilol
What drugs have β2 Antagonist activity?
Propranolol, Labetalol, Carvedilol