Funct Flashcards

(17 cards)

1
Q

What is the function of the nucleolus?

A

Produces ribosomes

The nucleolus is a prominent sub-nuclear structure involved in ribosome biogenesis.

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2
Q

What is the optimal pH range for lysosomal enzymes?

A

4.5 - 5.0

This acidic environment is crucial for the activity of hydrolytic enzymes within lysosomes.

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3
Q

What is the primary role of lysosomes in a cell?

A

Waste disposal system of the cell

Lysosomes digest various macromolecules and cellular debris.

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4
Q

What types of macromolecules do lysosomes digest?

A
  • Peptides
  • Nucleic acids
  • Carbohydrates
  • Lipids

Lysosomes contain enzymes specifically for the hydrolysis of these macromolecules.

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5
Q

What is autophagy?

A

Fused with phagosomes to digest large-damaged structures

Autophagy is a cellular process that recycles cellular components.

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6
Q

What is the role of lysosomes in phagocytosis?

A

Virus/bacterial lysis

Macrophages utilize lysosomes to break down pathogens they engulf.

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7
Q

What is the main function of peroxisomes?

A

Breaking down excess fatty acids to acetyl CoA

Peroxisomes also play a role in detoxifying hydrogen peroxide.

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8
Q

What does beta oxidation in peroxisomes refer to?

A

Breaking down excess fatty acids

This process converts fatty acids into acetyl CoA, a key metabolic intermediate.

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9
Q

What is one of the roles of peroxisomes in lipid metabolism?

A
  • Synthesis of cholesterol
  • Synthesis of bile acids

Peroxisomes are involved in various lipid metabolic processes.

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10
Q

How do peroxisomes contribute to purine nucleotide metabolism?

A

Breakdown of excess purine nucleotides (AMP, GMP) to uric acid

This process helps regulate purine levels in the cell.

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11
Q

What is the role of peroxisomes in the nervous system?

A

Participate in the synthesis of the lipids used to make myelin sheath of neurons

Myelin is crucial for proper neuronal function and signal transmission.

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12
Q

What are the main functions of mitochondria?

A
  • Regulation of cellular metabolism
  • Cellular proliferation
  • Apoptosis - programmed cell death

Mitochondria are often called the powerhouses of the cell due to their role in energy production.

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13
Q

What is the endomembrane system?

A

A system of developmentally related membranes

This system includes various organelles and membranes involved in protein and lipid synthesis.

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14
Q

Which organelles are included in the endomembrane system?

A
  • Cell membrane
  • Nuclear membrane
  • Endoplasmic reticulum
  • Golgi apparatus
  • Vesicles
  • Vacuoles

These components work together in the transport and processing of biomolecules.

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15
Q

What is the role of the rough endoplasmic reticulum?

A

Protein synthesis

The rough ER is studded with ribosomes, which are the sites of protein production.

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16
Q

What is the relationship between ribosomes and mRNA?

A

Ribosomes bind mRNA and tRNA to decode it

This process is essential for translating genetic information into proteins.

17
Q

What distinguishes free ribosomes from those attached to the endoplasmic reticulum?

A

Free ribosomes synthesize proteins to be exported from the cell

Attached ribosomes primarily synthesize proteins destined for secretion or for use within the cell.