Functional GI Disorders Flashcards

1
Q

describe functional GI disorder

A
  • no detectable pathology

- related to to gut function

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2
Q

prognosis of functional GI disorders

A

long term prognosis

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3
Q

types of functional GI disorders

A

oesophageal spadm

non-ulcer dyspepsie

biliary dyskinesia

IBS

slow transit constipation

drug related effects

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4
Q

how are the majority of functional GI disorders diagnosed

A

history

examination

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5
Q

nausea

A

the sensation of feeling sick

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6
Q

retching

A

dry heaves

Antrum contracts, glottis closed

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7
Q

vomiting

A

contents expelled

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8
Q

chemoreceptor trigger zone function

A

detects changes in the body and communicates them to the vomiting centre to initiate vomiting

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9
Q

factors that can tigger vomiting centre

A
  • receptors for opiates
  • digoxin
  • chemotherapy
  • uraemia
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10
Q

type of cause if vomiting occurs immediately after eating food

A

psychogenic

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11
Q

type of cause if vomiting occurs 1 hour after eating food

A
  • pyloric obstruction

- motility disorders

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12
Q

type of cause if vomiting occurs

12+ hours after eating food

A

obstruction etc.

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13
Q

functional causes of vomiting

A

drugs

pregnancy

migraine

cyclic vomiting syndrome

alcohol

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14
Q

psychogenic vomiting features

A
  • often young women
  • often for years
  • no preceding nausea
  • self induced?
  • Appetite usually not disturbed but may lose weight
  • often stops shortly after admission
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15
Q

functional diseases of lower GI tract

A

IBS

slow transit constipation

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16
Q

physical examination for functional disease

A
  • look for systemic disease
  • careful abdominal examination
  • rectal examination
17
Q

assessing patient ALARM symptoms?

A
  • Age >50 years
  • short symptom history
  • unintentional weight loss
  • nocturnal symptoms
  • male sex
  • family history of bowel/ ovarian cancer
  • anaemia
  • rectal bleeding
  • recent antibiotic use
  • abdominal mass
18
Q

investigations for functional disease

A
  • FBC
  • Blood glucose
  • U+E
  • Thyroid status
  • Coeliac serology
  • FIT testing
  • sigmoidoscopy
  • colonoscopy
19
Q

primary aetiologies of constipation

A
  1. systemic
  2. neurogenic
  3. organic
  4. functional
20
Q

organic aetiology of constipation

A
  • strictures
  • tumours
  • diverticular disease
  • proctitis
  • anal fissure
21
Q

functional aetiology of constipation

A
  • megacolon
  • idiopathic constipation
  • depression
  • psychosis
  • institutionalised patients
22
Q

systemic aetiology of constipation

A
  • diabetes mellitus
  • hypothyroidism
  • hypercalcaemia
23
Q

neurogenic aetiology

A
  • autonomic neuropathies
  • parkinsons
  • strokes
  • multiple sclerosis
  • spina bifida
24
Q

types of abdominal pain

A

vague
bloating
burning
sharp

25
causes of bloating
wind flatulance relaxation of abdominal wall muscles mucus in stool upper and other GI symptoms
26
calprotectin
released by inflamed gut mucosa used for differentiating IBS from IBD
27
describe the bowel with regards to motility
its a muscular tube that squeezes content from one end to another
28
what happens to bowel motility in IBS C vs D
C - muscular contractions may be stronger and more frequent than normal. D - contractions reduced
29
what can gut contractions be triggered by in IBS
walking eating
30
describe the brains involvement with the gut in IBS
the brain is able to hear messages from the gut such as hunger or the urge to go to the toilet
31
what can influence IBS bowl
psychosocial physiological