Functional Renal Flashcards

(58 cards)

1
Q

Typical rate for GFR

A

125 ml/min

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2
Q

first step in urine formation

A

glomerular filtration

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3
Q

water and solutes are filtered into the capsule due to

A

hydrostatic pressure

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4
Q

where does tubular reabsorption occur?

A

PCT

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5
Q

nutrients, ions, majority of the water is reabsorbed back into the blood by … throughout…

A

passive and active mechanisms
through PCT, loop of Henle and DCT

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6
Q

which process is an active one?

A

tubular secretion

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7
Q

capacity of bladder

A

700-800ml

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8
Q

where do we find the functional or parenchymal tissue in the kidney?

A

medulla

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9
Q

blood back to filtrate

A

tubular secretion

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10
Q

filtrate back to blood

A

tubular reabsorption

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11
Q

functional RPs

A

MAG3, DTPA

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12
Q

morphological RPs

A

DMSA, Gluco

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13
Q

tubular secreted agent

A

MAG3

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14
Q

glomerular filtrated agent

A

DTPA

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15
Q

agent that has the higher protein binding

A

MAG3

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16
Q

why does MAG3 have high T:NT?

A

can’t diffuse into extravascular spaces

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17
Q

agent of choice for obstruction cases or highly impaired renal functions

A

MAG3

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18
Q

agent used for ERPF

A

MAG3

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19
Q

mag3 first pass extraction = %?
dtpa first pass extraction = %?

A

mag3 = 50%
dtpa = 20%

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20
Q

70% dose excreted in urine at 30mins

A

mag3

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21
Q

50% of dose excreted in urine at 2hrs

A

dtpa

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22
Q

agent used for GFR

A

dtpa

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23
Q

indication for functional renal scans

A
  • for baseline or followup of kidney differential function and PERFUSION
  • trauma, failure
  • eval transplant (rejection, urine leak, atn)
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24
Q

patient prep for functional renal scans

A
  • well hydrated
  • void before imaging
25
what is the minimum amount of water a patient needs to have?
300-500ml
26
kidneys are found in the ___ FOV
top of the FOV
27
method of admin
IV bolus
28
dose of RP
90-370 MBq
29
2 sequential phasing phase 1
renal perfusion (flow)
30
2 sequential phasing phase 2
function (dynamic)
31
relative time frame for imaging
flow = 2 mins dynamic = 25-30 mins post-void static = 2.5 mins
32
renogram
TAC that shows perfusion uptake and excretion of RP in each kidney
33
aorta ROI
assesses perfusion and quality of bolus
34
dynamic function renogram has 3 phases
1. blood flow 2. cortical function 3. clearance
35
peak activity in healthy, hydrated patient
3-5 min post injection
36
bladder is seen by ..
4-8 mins
37
blood flow aka
perfusion, vascular
38
cortical function aka
cortical uptake, parenchymal, tubular concentration, secretory
39
clearance aka
excretion, collecting system
40
time to peak
by 5 mins (typically, 3-5 min)
41
20 min/max count ratio
ratio <0.35
42
what is the 20min/max count ratio measuring?
residual cortical activity based on counts at 20 mins to max counts = transit time in kidney
43
differential cortical retention
difference <20%
44
T1/2 excretion
<20 mins (typically, 8-12 mins)
45
what does T1/2 represent?
time for half the peak activity to be cleared from the kidney
46
what is differential cortical retention?
% retained in each kidney at 15 or 20 mins
47
differential renal function
each kidney 45-55%
48
what is differential renal function
comparing activity in each kidney at 2-3 mins DTPA or 1.5-2.5 mins MAG3
49
which kidney is slightly lower than the other?
right
50
renal calyces and pelvis usually begin filling by
3 mins
51
blood flow to kidneys is normally seen within ____ of ab. aorta visualization
2-5 secs
52
activity visualized in renal parenchyma by
1-5 mins
53
if a patient was dehydrated, what would we see on the renogram?
elevation of excretion slope
54
increased liver/spleen activity can indicate...
renal failure
55
allograft
transplant from same species
56
normal results for renal transplant flow:
RP bolus to get to transplant at almost the exact time seen in the iliac vessels
57
normal results for renal transplant function:
max uptake 3-5 min bladder by 4-8 min prompt peak and rapid clearance
58
normal results for renal transplant function:
function: