Fundamental Principles of Pharmacology

Question 1

what the drug is licensed to treat.

Answer 1

Indication

Question 2

to achieve its therapeutic effect.

Answer 2

Mechanism of action

Question 3

expected reactions that often happen when a patient takes a drug.

Answer 3

Side effects

Question 4

unintended, or potentially life-threatening effects

Answer 4

adverse effects

Question 5

how an organism, such as humans, affects a drug.

Answer 5

Pharmacokinetics

Question 6

what the drug does to the body.

Answer 6

Pharmacodynamics

Question 7

are proteins – chemical structures in the body.

Answer 7

Receptors

Question 8

activating the switch (“receptor”).

Answer 8

agonist

Question 9

deactivated the switch (“receptor”)

Answer 9

Antagonist

Question 10

elaborate bodily system that is involved in the metabolism of drugs.

Answer 10

CYP 450 is a superfamily of enzymes

Question 11

responsible for metabolizing over half of all prescribed drugs.

Answer 11

CYP3A4

Question 12

can interact with other drugs, with food, and with disease.

Answer 12

Drug Interactions

Question 13

When a drug first comes on the market, it has a patent.

Answer 13

Generic versus Branded Drug

Question 14

medicine is the time it takes for the total amount of drug in the body to reduce by 50 percent.

Answer 14

Half-life