Fundamentals: Chapter 31 Flashcards

1
Q

What is the chemical name of a medication?

A

An exact description of its composition and molecular structure

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2
Q

What is the generic name of a medication?

A

the name given to a medication by the manufacturer who first develops it

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3
Q

What is the trade name of a medication?

A

the name under which a manufacturer markets a medication

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4
Q

What is a medication classification?

A

indicates the effect of the medication on a body system, the symptoms the medication relieves, or its desired effect

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5
Q

What is the study of how medications enter the body, reach their site of action, metabolize, and exit the body?

A

pharmacokinetics

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6
Q

What is the passage of medication molecules into the blood from the site of medication administration?

A

absorption

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7
Q

What route of administration produces the most rapid absorption?

A

IV

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8
Q

When is medication absorption complete?

A

When it is absorbed into the blood

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9
Q

Which three factors effect the ability of a medication to dissolve?

A

Blood flow to the site of administration

Body surface area

Lipid solubility

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10
Q

How does body surface area effect absorption of medications?

A

large surface area = faster absorption rate

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11
Q

Which three factors effect the distribution of a medication?

A

Circulation

Membrane permeability

Protein binding

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12
Q

What kind of medications can pass through the blood-brain barrier?

A

fat-soluble

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13
Q

How does protein binding effect distribution of a medication?

A

medications bound to albumin cannot exert pharmacological activity

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14
Q

How does age effect protein binding?

A

Older adults have less protein, therefore less medication binds to protein which leads to increased med activity and/or toxicity.

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15
Q

What happens to medication once it reaches the site of action?

A

it becomes metabolized into a less active or inactive form that is easier to excrete

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16
Q

What is the term for the removal of the toxic quality of a substance?

A

detoxify

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17
Q

Where does most biotransformation occur?

A

liver

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18
Q

Where is a medication excreted after metabolism?

A

Kidneys, Liver, bowel, lungs, and exocrine glands

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19
Q

What is the purpose of deep breathing and coughing?

A

helps patients to eliminate anesthetic gases more rapidly

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20
Q

What is the main organ for medication excretion?

A

kidney

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21
Q

What are the types of medication actions?

A

Therapeutic

Adverse

Side

Toxic

Idiosyncratic

Allergic

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22
Q

What is the therapeutic effect?

A

the expected or predicted physiological response to a medication

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23
Q

What is a side effect?

A

predictable and often unavoidable secondary effects produced at a usual therapeutic dose

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24
Q

What are adverse effects?

A

unintended, undesirable, and often unpredictable severe responses to medications

25
What are idiosyncratic reactions?
patient overreacts or under-reacts to a medication has a reaction different from normal
26
What is a severe allergic reaction characterized by?
sudden constriction of bronchiolar muscles, edema of the pharynx and larynx, server wheezing, SOB
27
What is a synergistic effect?
when two medications have a combined effect that is greater than the effect of medications when given separately
28
What are time critical medications?
meds in which early or delayed administration of maintenance doses (30 min before/after) will most likely cause harm or result in sub-therapeutic responses in a patient.
29
What is the time it takes after a medication is administered for it to produce a response?
Onset
30
What is the time it takes for a medication to reach it's highest effective concentration?
Peak
31
What is term for when the minimum blood serum concentration of a medication reached just before the next scheduled dose?
Trough
32
What is the time during which the medication is present in concentration great enough to produce a response?
Duration
33
What is the term for when the therapeutic blood serum concentration of a medication has been reached and is maintained after repeated doses?
Plateau
34
What is the easiest and most commonly used route for medication administration?
Oral
35
When giving a sublingual medication, what is an important nursing education for the patient?
Do not drink anything until the medication is completely dissolved
36
When giving buccal meddications, what is an important nursing education for the patient?
alternate cheeks with each subsequent dose, do not chew or swallow, do not take any liquids
37
Explain the epidural route:
medications administered in the epidural space via a catheter
38
Explain the intrathecal route:
medications administered through a catheter placed in the subarachnoid space or one of the the ventricles of the brain.
39
Explain the Intraosseous route:
infusion of medication directly into the bone marrow
40
Explain intraperitoneal route:
medications administered into the peritoneal cavity
41
Explain the intrapleural route:
a syringe and needle or a chest tube is used to administer medications directly into the pleural
42
What is the pleurodesis?
instilling medications through the intraplural route that help resolve persistent pleural effusion
43
Explain the intraarterial route:
medications adminstered directly into the arteries
44
What situations are intraarterial infusions common?
in patients who have arterial clots
45
What are the 5 ways nurses can administer medications to mucous membranes?
Direct via liquid or ointment Inserting into body cavity Instilling fluid into a body cavity Irrigating a body cavity Spraying into body cavity
46
Pediatric IM doses do not usually exceed ______ml in small children and ______ml in infants.
1ml 0.5ml
47
Pediatric subcutaneous doses do not usually exceed _____ml.
0.5ml
48
To what decimal places are pediatric doses usually rounded to?
thousandths
49
Who can write a medication order?
Physician Nurse Practitioner Physician's Assistant
50
Within how much time of receiving a "now order" must the nurse administer the medication?
90 minutes
51
What are the 4 steps to medication reconciliation?
1. Verify 2. Clarify 3. Reconcile 4. Transmit
52
What are the best subcutaneous injection sites?
outer posterior aspect of the upper arms, the abdomen from below the costal margins to the iliac crests, and the anterior aspects of the thighs
53
What is the angle of insertion for IM injections?
90º
54
What is the angle of insertion for subcutaneous injections?
45º-90º
55
What is the angle of insertion for intradermal injections?
15º
56
What are the best intramuscular (IM) injection sites?
Ventrogluteal Vastus Lateralis Deltoid
57
What is the most dangerous route method for administering medications?
IV bolus, or "push"
58
When giving IM injections, what technique is used to protect subcutaneous tissues from irritating parenteral fluids?
Z-track method