Fungal infection Flashcards
(4 cards)
1
Q
How do fungal evade phagocytosis
A
cover the pamps like B-glucans by manoproteins
no detection by immune system
2
Q
How do fungal invade complement
A
app1 prtein blocks Complement receptor 3 no osonisation
3
Q
Evasion of phagiocytosis by fungus
A
conversion from yeast to hypahe - too big to swallow
4
Q
how dies fungus lead to immunosupression
A
induces IL-10 release with TLR-2. this increasing Treg prodution leading to immunosupression
