Fungal infections Flashcards
1
Q
What is the dosage regimen for nystatin
A
1 drop qds for 7 days and continued for 48 hours after lesions have resolved
2
Q
How do polyene antifungals work
A
They bind to ergosterol in fungal membranes. This makes the membranes leaky
3
Q
what class of antifungal is nystatin
A
Polyene
4
Q
How to imidazole and triazole antifungals work
A
They inhibit ergosterol synthesis
This prevents fungal cell membrane synthesis, growth and replication
5
Q
Which antifungal is cautioned in liver disease
A
Fluconazole
6
Q
Can fluconazole be used for thrush in pregnancy ?
A
No
It should be avoided during pregnancy
