FUNGAL INFECTIONS

Question 1

How would one treat Candida leukoplakia?

Answer 1

Refer to specialist as it is potentially pre-malignant

Question 2

What is the prescription for nystatin?

Answer 2

1ml after food four times daily for 7 days

100,000 units / ml

Rinse around mouth then leave close to lesion for 5 minutes

Continue 48 hours after lesion has fully healed

Question 3

What is the prescription for miconazole?

Contra indications?

Answer 3

Miconazole 20mg/g

1 pea sized amount, after food, four times daily, and use for 7 days after lesion has healed

Statins and warfarin

Question 4

Prescribe fluconazole

Answer 4

1 capsule daily, 50mg capsule

Use for maximum of 14 days

Question 5

How do Azole medications act on candida?

Answer 5

Inhibit synthesis of ergosterol, an essential component of the fungal cell membrane.

Causes structural and functional damage to cell membrane and the cell becomes weakened

Question 6

How does nystatin act on candida?

Answer 6

Binds to ergosterol in the cell membrane and causes pores and lysis of the candida cell