Fungal & Viral Infections Flashcards
(24 cards)
What is the treatment for Aspergillosis?
Voriconazole
What is the treatment for Cryptococcosis?
Amphotericin B
What are the treatments for vaginal thrush?
Clotrimazole / Fluconazole
If resistant, use Itraconazole
What are the treatments for oral thrush?
Nystatin / Miconazole / Fluconazole
If resistant, use Itraconazole
What is the recommended therapy for skin and nail infections?
Topical therapy
If topical not appropriate, use systemic therapy (itraconazole, terbinafine)
Where can Tinea (ringworm) be found?
Head, body, groin, feet, nails
What is the treatment for Tinea?
Topical antifungal cream or terbinafine
What is the treatment for nail region infections?
Terbinafine or amorolfine nail lacquer
Apply once weekly for up to one year
When should a patient be referred to a GP for nail infections?
If under 18, more than 2 nails affected, diabetic, pregnant, or breastfeeding
What are the side effects of Fluconazole, Itraconazole, Ketoconazole, and Voriconazole?
QT prolongation and hepatotoxicity
Which antifungal medication has the highest risk of hepatotoxicity?
Ketoconazole
What enhances the bioavailability of Itraconazole?
Carbonated drinks
What is a significant risk associated with Ketoconazole?
Life-threatening hepatotoxicity
What should be avoided due to the risk of phototoxicity with Voriconazole?
Sunlight exposure
What is the recommended procedure for administering Amphotericin B intravenously due to anaphylaxis risk?
Test dose with 30 min observation
use prophylactic antipyretics or hydrocortisone in pts with previous reactions
why is it important to maintain the same formulation of amphotericin B
serious harm and fatal overdoses have occurred
Serious harm and fatal overdoses have occurred with changes
What is a notable side effect of Terbinafine?
Hepatotoxicity
What are the treatments for Varicella zoster, herpes zoster, shingles and Chickenpox?
Acyclovir / valaciclovir (pro-drug)
What should patients aged 14 years and older take for Chickenpox?
Antiviral within 24 hours of onset
What medications should never be given to patients with Chickenpox?
Ibuprofen (NSAID) or aspirin
What are the symptoms of Herpes/Shingles?
Tingling sensation, burning, fluid-filled blisters
How does Shingles typically present on the body?
Follows the pattern of individual nerves on one side of the body
can look like a belt/half belt around rib cage or torso
