Fungi Basics Flashcards
Fungal cell wall vs. bacterial cell wall
Fungal membrane has…
Chitin/Mannan vs. Peptidoglycan
Sterols (bacteria don’t have these)
Clinical classification of mycoses
- superficial (e.g. dermatophytes)
- deep or systemic
- opportunistic
Candida spp.
- Where is it found?
- associated diseases
- Part of normal human flora
- Superficial or mucocutaneous candidiasis
- systemic infection
Cryptococcus spp.
- Where is it found?
- Who gets infected?
- What systems are involved?
- Name of vancouver island strain
- bird droppings
- Usually only immunocompromised, but can be immunocompetent with very high dose
- Pulmonary/CNS, hematogenous spread
- C. gattii
Pneumocystis jirovecii
- reservoir
- formerly known as?
- indicative of?
- Humans (most seropositive by 4 y.o)
- PCP
- PC/PJ pneumonia is an AIDS defining condition
Define mucormycosis
- who gets it?
Mycosis caused by organisms in the order of mucorales.
Immunocompromised people get it.
Histoplasma capsulatum
- where is it found
- types of disease presentation
- bat droppings, eastern and central US
- Asymptomatic, acute benign respiratory, acute disseminated, chronic disseminated, chronic pulmonary (resembles TB)
Blastomyces dermatitidis
- where is it found
- incubation time
- symptoms
- forests in eastern US/Canada (hunters/trappers at risk)
- 3-15 weeks
- blastomycosis similar to flu, but can disseminate to bone and skin
Coccidiodes immitis
- where is it found
- incubation time
- symptoms
- semi-arid areas of california to southern texas
- 1 wk to 1 month
- flu-like symptoms, can be TB like
Dermatophyte definition
Closely related group of fungi that obtain nutrients from keratin (skin and nails)
Define tinea
AKA: ring worm. Most caused by dermatophytes.
-classified by anatomical area infected
Malassezia spp.
- causes?
- where does it live?
Tinea versicolor
Part of normal flora
