G Flashcards
? (30 cards)
What is the primary purpose of the excretory system?
To filter and remove wastes from the body fluids of an organism
What are the three main layers of the kidney?
- Cortex (outer layer of connective tissue)
- Medulla
- Renal Pelvis (connected to the ureter)
What is the primary site of filtration in the kidney?
Medulla
How many nephrons does a kidney contain approximately?
About 1 million nephrons
What is the glomerulus?
The first part of the nephron where blood plasma and its solutes flow into the Bowman’s capsule
Which substances do not normally pass from the glomerulus into the Bowman’s capsule?
- Proteins
- Erythrocytes (RBCs)
- Platelets
What is the sequence of structures that filtrate passes through after the Bowman’s capsule?
Proximal tubule → Loop of Henle → Distal tubule → Collecting duct → Ureter → Bladder
What substances are reabsorbed at the proximal tubule?
- HCO3-
- NaCl
- H2O
- Nutrients
- K+
What occurs at the descending loop of Henle?
H2O is reabsorbed into capillaries
What is reabsorbed in the ascending loop of Henle?
NaCl is reabsorbed into the capillaries
What happens at the distal tubule?
HCO3-, NaCl, and H2O are reabsorbed into capillaries
What is the role of the collecting duct?
Reabsorbs NaCl, H2O, and some urea into capillaries
What is active transport?
The process by which substances are moved against their concentration gradient
What type of molecules are secreted back into the nephron?
- H+ (acids)
- Excess minerals (e.g., Na+, K+)
- Nitrogenous wastes (e.g., urea, creatinine, uric acid, ammonia)
- Drugs
What is Antidiuretic Hormone (ADH)?
A hormone that increases water reabsorption in the distal tubule and collecting duct
What triggers the release of ADH?
Low blood pressure, dehydration, or during sleep
What hormone is released by juxtaglomerular cells when low blood flow is detected?
Renin
What does renin convert angiotensinogen into?
Angiotensin I
What is the role of ACE (angiotensin converting enzyme)?
Turns angiotensin I into angiotensin II
What does angiotensin II stimulate?
- Vasoconstriction
- Release of ADH
- Release of aldosterone
What is aldosterone’s function?
Stimulates thirst and increases NaCl and water reabsorption in the nephron
What are kidney stones?
Mineral solutes in the blood that precipitate into stones causing damage to the kidney
What condition results from low insulin levels leading to high blood glucose?
Diabetes Mellitus
What is the effect of high glucose concentrations in nephron filtrate?
Shifts osmotic balance, drawing water into urine instead of back into capillaries