gas exchange Flashcards
(50 cards)
what is fick’s law?
surface area x difference in conc / diffusion distance
name three features of an efficient gas exchange system
● large surface area
● short diffusion distance
● steep conc gradient (maintained by blood supply or ventilation)
what is ventilation?
breathing
what is the trachea?
wind pipe
what is the thoracic cavity?
space where the lungs are
explain the human gas exchange system
● as you breathe in, air enters trachea
● trachea splits into 2 bronchi
● each bronchus branches off into smaller tubes called bronchioles
● bronchioles end in small air sacs called alveoli
● ribcage, intercostal muscles and diaphragm work together to move air in and out
explain inspiration
● external intercostal muscles contract
● ribcage - moves upwards and outwards
● diaphragm contracts to flatten
● increasing volume of thoracic cavity
● as volume increases, lung pressure decreases (to below atmospheric pressure)
● air flows down the trachea and into lungs down pressure gradient
what does inspiration require?
energy (active)
explain expiration
● external intercostal and diaphragm muscles relax
● ribcage moves downward and inwards
● diaphragm becomes curved
● volume of thoracic cavity decreases, causing pressure to increase (to above atmospheric pressure)
● air forced down pressure gradient and out of lungs
what does expiration not require?
energy (passive)
explain forced expiration
● external intercostal muscles relax
● internal intercostal muscles contract
● pulling ribcage further down and in
● movement of 2 sets of intercostal muscles are antagonising
what are alveoli made from?
alveolar epithelium
what is the alveolar epithelium made of?
a single layer of thin, flat squamous cells
how does human gaseous exchange happens in the alveoli?
● oxygen diffuses out alveoli, across the alveolar epithelium and capillary endothelium
● into haemoglobin in red blood cells
● carbon dioxide diffuses from blood across capillary endothelium and alveolar epithelium and into alveoli and is breathed out
● movement happens down a diffusion gradient
what is the capillary endothelium?
type of epithelium that forms the capillary wall
how does human gaseous exchange happens in the alveoli? (simplified)
● oxygen - trachea - bronchi - bronchioles - alveoli
● happens down a pressure gradient
● alveoli - diffuse across alveolar epithelium and capillary endothelium - capillary - haemoglobin in blood
● happens down a diffusion gradient
how are alveoli adapted for gas exchange?
● short diffusion distance - alveolar epithelium is made of squamous cells (thin exchange surface)
● large surface area - large number of alveoli means there’s a large surface for gas exchange and folds in alveolar epithelium
● steep concentration gradient of O2 and CO2 between alveoli and capillaries
● capillaries give good blood supply
what is the composition of gases inhaled?
● higher conc of O2
● N2 stays the same
● lower conc of CO2
what is the composition of gases exhaled?
● lower conc of O2
● N2 stays the same
● higher conc of CO2
what is tidal volume?
● tidal volume is the volume of air in each breath
● average 0.4 - 0.5dm^3
what is forced expiratory volume (FEV1)?
maximum volume of air that can be breathed out in 1 second
what is forced vital capacity (FVC)?
maximum volume of air that can be breathed forcefully out after a deep breath
what is pulmonary ventilation?
● volume of air ventilated by the lungs in 1 minute
● PV (dm^3) = tidal volume x ventilation rate
what is ventilation rate?
● number of breaths per minute
● average 15