Gastric cancer Flashcards
1
Q
Risk factors
A
H.pylori (triggers inflammation of the mucosa leading to atrophy and intestinal metaplasia)
Atrophic gastritis
Diet (salt and salt-preserved foods, nitrates)
Smoking
Blood group
2
Q
Features
A
Abdo pain
Weight loss and anorexia
Nausea and vomiting
Dysphagia
Overt upper GI bleeding in minority of cases
Virchow’s node (left supraclavicular)
Sister Mary Joseph’s node (periumbilical)
3
Q
Diagnosis
A
OGD
Signet ring cells seen (contain large vacuole of mucin which dispalces nucleus to one side)
4
Q
Staging
A
CT
5
Q
Management
A
Endoscopic mucosal resection
Partial gastrectomy
Total gastrectomy
Chemotherapy
