GASTRO

Question 1

Multiple duo/ jejunal ulcers with chronic diarhea
Vit b12 def

Answer 1

Zollinger ellison

Question 2

Man of any age with unexplained Hb<110

Answer 2

UGI and colonoscopy

Question 3

Crohns Drugs

Answer 3

1- Steroids
2- Other Azo , mercaptopurine, metx, ,mesalazine, sulphasalazine
3- Biologics- infliximab( r/o TB), adalimubab, golimubab

Question 4

FAP extra colonic ftrs

Answer 4

Cong hypertrophy Retina
dental -supernumeray teeth,
Skull/ manduble osteoma
fibroma/ epidemoid cyst

Question 5

Pyoderma gangrenosum asociated conditions

Answer 5

IBD, PBC, PSC ( MC men) , RA, Heam malignancy

Question 6

coeliac derma ds

Answer 6

Dermatitis herpetiformis

Question 7

CS- Sudden RUQ pain, rapid ascites, hepatomegaly, AKI, Fulminant Liver failure

Answer 7

Bud- chiari- initial inv - Dopller usg

Question 8

Bleeding PR with Tc 99 scintigraphy +

Answer 8

Meckels diverticulum

Question 9

PBCserology

Answer 9

M2 sub unit of AMA
AMA
ANA

Question 10

AI Hepatitis serology

Answer 10

ty 1- ANA, ASMA
TY 2- Anti liver kidney microsome antibody
Anti liver cytosol antibody

Question 11

cs-Fever night sweat fatigue weight loss Hepatospleno- initial and def inv

Answer 11

Visc Leishmaniasis
Initial- Direct agglutination ,Rk 39
Gold std- LIVER BIOPSY

Question 12

Barrets eso histo

Answer 12

normal squamous to columnar epi

Question 13

pregnancy related
Intra hepatic cholestasis of pregnancy vs acute fatty liver of pregnancy

Answer 13

ICP- 2,3 Trimester hand/feet pruritis, RUQ pain
tx-udc, bil>100 deliver at 34 to 36 wk

AFLP- 3rd tri, n v jaundice RUQ pain LF
ascites aki hypoglycemia encephalopathy coagulopathy
Tx - immediate delivery, Liver transplant if needed

Question 14

Long term ppi diarhea?

Answer 14

Lymphocytic colitis

Question 15

MALT with H pylori initial tx?

Answer 15

eradicate h pylori

Question 16

Dermatomyositis tumors

Answer 16

Bronchial, esophagial

Question 17

Muliple small bowel resection plus watery diarhea

Answer 17

Short bowel syndrome, tx- cholestyramine

Question 18

Cowdens ds ftrs

Answer 18

AD
Hamartoma- breast bowel thyroid uterus brain
skin hamartoma trichilemmoma sclerotic fibroma

Question 19

Puetz jegher

Answer 19

GI malig- Colorectal gastric SI
Other malig- breast cervical
Mucocutaneous pigmentation

Question 20

CS- age 60>
with unexplained anemia iron def anemia/ positive stool occult blood/ change in bowel habit

Answer 20

Endoscopy UGI + LGI

Question 21

aflp vs HELP

Answer 21

HELP- HTN present

Question 22

Anti epileptic causing acute pancreatitis

Answer 22

Valproate

Question 23

Medications causing pancreatitis

Answer 23

Tetracycline, Metronidazole, lamivudine, sulphmethoxazole, INH
Pravastatin, simvastatin,
Amiodarone, codeine

Question 24

Adult with IDA 1st inv

Answer 24

Urinanalysis before endoscopy

Question 25

fmf ftrs

Answer 25

AR chr 16 Acute abdominal pain with ftrs of peritonitis and fever , each attack upto 72 hrs other - pluritis/ pericarditis, synovitis and eryspeliod rash Bloods - Acute phase reactants H/o multiple sx T- Colchicine

Question 26

Before 1990 blood transfusion, which infection to look for

Answer 26

hep c

Question 27

most useful initial dx inv in hereditary hemochromatosis-

Answer 27

Genetic screening

Question 28

coeliac histology

Answer 28

sub total villuous atrophy

Question 29

Crohns histo

Answer 29

Transmural Inflammation: entire thickness Skip Lesions: Granulomas: Non-caseating Deep Ulcers: Cobblestone Appearance: Lymphoid Aggregates: Found in the submucosa and deeper layers.

Question 30

uc histo

Answer 30

Mucosal and Submucosal Inflammation: Continuous Inflammation: Affects the colon Crypt Abscesses: Neutrophils infiltrate the crypts, Architectural Distortion: No Granulomas: Mucin Depletion:

Question 31

Dermatitis herpetiformis rash

Answer 31

Pruritic and blistering polymorphic rash over elbow, knee, ?extensor

Question 32

Gastro duodenal stricture in crohns without obstruction tx

Answer 32

Immunosup with predni then stabilize with AZT

Question 33

HEP B serology

Question 34

Kings college criteria ALF

Answer 34

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