Gastroduodenal Tumors

Question 1

most common benign tumor of the stomach

Answer 1

Epithelial polyps

Question 2

most common gastric polyp

Answer 2

Hyperplastic (regenerative

Question 3

Three most common primary malignant gastric neoplasms

Answer 3

Adenocarcinoma (95%)
Lymphoma (4%)
Malignant Gastrointestinal Stromal Tumor (GIST) (1%)

Question 4

most common genetic abnormalities in sporadic gastric cancer affect

Answer 4

p53 and COX-2 genes

Question 5

Most common precursor of gastric CA the intestinal subtype

Answer 5

Atrophic Gastritis

Question 6

common cell type arising in the stomach

Answer 6

Epithelial cell stromal GIST

Question 7

most common site of duodenal CA

Answer 7

duodenal bulb

Question 8

most common mesenchymal tumors in the small intestine

Answer 8

GI stromal tumors (GIST)

Question 9

Five types of benign epithelial polyps

Answer 9

adenomatous, hyperplastic (regenerative), hamartomatous, inflammatory, and heterotopic

Question 10

largest artery of the stomach

Answer 10

left gastric

Question 11

where most of gastric CA arises

Answer 11

pyloric antrum

Question 12

type of polyp that may undergo malignant transformation

Answer 12

adenomatous polyp

Question 13

Benign submucosal fatty tumors that are usually asymptomatic, found incidentally on upper GI series or esophagogastroduodenoscopy (EGD)

Answer 13

lipoma

Question 14

4 subtypes of gastric ca

Answer 14

polypoid
fungating
ulcerative
scirrhous

Question 15

common presentation of Scirrhous type

Answer 15

Linitis Plasctica

Question 16

gold standard for diagnostic evaluation of gastric ca

Answer 16

UGIE

Question 17

to demonstrate the depth of the tumor in terms of its involvement in relation to the layers of abdominal wall; more sensitive than CT scan in local staging;

Answer 17

Endoscopic UTZ

Question 18

• Generally accepted universal precursor to gastric adenocarcinoma

Answer 18

Dysplasia

Question 19

Examines extent of invasion of tumor and involvement of lymph nodes

Answer 19

EUS (Endoscopic Ultrasonography

Question 20

BEST WAY to stage tumor LOCALLY because it has 80% validity in assessing depth of tumor penetration

Answer 20

EUS (Endoscopic Ultrasonography)

Question 21

when is PET scan best used

Answer 21

If gastric CA has distant mestatasis

Question 22

Gold standard treatment for gastric Ca

Answer 22

Radical Subtotal Gastrectomy For Gastric Cancer

Question 23

INDICATIONS FOR SURGERY IN ADVANCE STAGE GASTRIC CANCER

Answer 23

1. Perforation
2. Obstruction
3. Bleeding needing continuous transfusion

Question 24

mode of spread of gastric leiomyosarcoma

Answer 24

BLoodstream

Question 25

Malignant tumor of the smooth muscle

Answer 25

GASTRIC LEIOMYOSARCOMA

Question 26

where ampulla of vater is located in the duodenum

Answer 26

descending limb

Question 27

hypersecrete histamine

Answer 27

Enterochromaffin like cells (ecl)

Question 28

Patient swallows a capsule equipped with a camera which record images of the intestines

Answer 28

Capsule endoscopy

Question 29

Visualize layers of intestinal wall involved by the lesion

Answer 29

Endoscopic Ultrasound

Question 30

Whipple’s operation – resection of the

Answer 30

``` Head of pancreas Distal stomach Duodenum Gallbladder Common bile duct ```

Question 31

gold standard test for helicobacter pylori

Answer 31

Histologic examination of an antral mucosal biopsy using special stains

Question 32

Useful in the evaluation of the patient with anomalous epigastric symptoms

Answer 32

Antrooduodenal Motility Testing and Electrogastrography

Question 33

alternative to Imatinib

Answer 33

Sunitinib

Question 34

tyrosine kinase inhibito

Answer 34

Imatinib

Question 35

lymphoma mostly occurs in the

Answer 35

ileum because it has the highest conc of lymphoid tissue

Question 36

most common site of GIST

Answer 36

stomach, SI 2nd

Question 37

classification of adenoma

Answer 37

tubula villous tubulovillous

Question 38

most agressive classificaiton of adenoma

Answer 38

villous

Question 39

high risk of developing hamartomatous polyps (have potentially malignant adenomatous foci)

Answer 39

Peutz-Jeghers Syndrome