gastroenterology Flashcards

(34 cards)

1
Q

What is the function of the GI tract?

A

Turn food into energy
Waste removal
Intake of water- hydration

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2
Q

What are key GI symptoms?

A

Vomiting
Weight loss
Jaundice
Malaena
Haematemesis
Abdominal pain
Diarrhoea

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3
Q

How do you take a history for dysphagia?

A

Duration
Solids/liquids
Pain
Weight loss
Previous med history
Meds
Cigarettes/alcohol

Could be oropharyngeal, oesophageal or gastric

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4
Q

What are oropharyngeal causes of dysphagia?

A

Salivary gland- Sjögren’s syndrome

Tongue- amyloidosis, hypothyroidism, MND

Upper oesophageal- cerebrovascular disease, MMD, Parkinson’s

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5
Q

What are oesophageal causes of dysphagia?

A

Benign mucosal disease- benign peptic structure, web (Plummer Vinson syndrome), Candida oesophagitis

Malignant mucosal disease- carcinoma

Motility disorders- spasm, achalasia, pouch

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6
Q

What is a pharyngeal pouch?

A

Defect between constrictor and transverse cricopharyneus muscle

Mostly asymptomatic
Diagnose- Barium swallow

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7
Q

What is achalasia?

A

Bird beak sign
Tapering of distal oesophagus

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8
Q

What are gastric causes of dysphagia?

A

Carcinoma

Outlet obstruction- peptic ulceration

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9
Q

How do we manage dysphagia?

A

Tx underlying cause

Nutritionally deplete- supplementation- oral, NG, PEG

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10
Q

What is GORD?

A

Gastro-oesophageal reflux disease

Excessive relaxation of lower oesophageal sphincter and raised intra-abdominal pressure

Heartburn, epigastric pain, acid reflux, waterbrash, N&V, tooth decay, asthma

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11
Q

How do we manage acid reflux?

A

Proton pump inhibitor (omeprazole, lansoprazole)

H2 receptor antagonists- tx symptoms

Lifestyle advice (weight loss, smoking cessation, reduce alcohol)

Surgery- fundoplication

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12
Q

What is a hiatus hernia?

A

Pressure gradient lost between abdominal and thoracic cavities

Can develop reflux symptoms

2 types- sliding hiatal hernia, paraoesophageal hernia

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13
Q

What is oesophageal manometery?

A

Use w 24 hr pH monitoring
Diagnoses refractory reflux disease
Used in motility disorders

Measure pressure profiles
Catheter and recording device
If falls below 4- reflux event

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14
Q

When might upper ab pain signify peptic ulceration?

A

Epigastric pain- can radiate to back

Gastric ulcer- worsened by food, weight loss, more like haematemesis
Duodenal ulcer- improved by eating, more likely vomiting

Complications- bleeding, perforation

Due to H. pylori, NSAIDs

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15
Q

How are peptic ulcers managed?

A

Treat the cause
Endoscopic tx
Surgery

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16
Q

When might upper ab pain signify gastric carcinoma?

A

Epigastric pain, weight loss, vomiting
Anyone over 40 w new onset symptoms
Can be asymptomatic
Gastroscopy + biopsy
Staging- CT/ultrasound
Tx= gastrectomy

17
Q

What are other causes of upper abdominal pain?

A

Non-ulcer dyspepsia- and nausea and bloating

Pancreatic carcinoma- and unremitting pain, weight loss and jaundice (usually palliative approach)

Pancreatitis- severe pain and vomiting (blood test and ultrasound/CT), long term opiate tx (middle age men, alcohol)

18
Q

What are causes of lower acute ab pain?

A

Consider location (RU, RL, LU, LL)

Inflammation (diffuse then localised), perforation (abrupt), obstruction

19
Q

How is acute ab pain managed?

A

Surgical referral
Usually kept NBM (nil by mouth)
IV antibiotics
Imaging USS/CT

20
Q

What is lower chronic ab pain?

A

Over 6 weeks
Organic/inorganic
Consider location and features
Management- difficult, analgesics, surgery

21
Q

What are the causes of vomiting?

A

Systemic illness (infection)
Drugs/alcohol
Centrally mediated
Psychiatric disorders
Oesophageal/gastric/small bowel disease
Colonic disease- obstruction (tumours/volvulus)

22
Q

How do we manage vomiting?

A

Identify underlying cause and treat
Antiemetics (cyclizine, metoclopramide)
PPI
CBT (therapy)

23
Q

What is acute diarrhoea?

A

3 or more loose/liquid stools a day
Change from normal bowel habit

Infection (bacterial/viral gastroenteritis)- Campylobacter, Salmonella, Shigella, E. coli
Drugs- antibiotics/alcohol/PPI
Food allergy/intolerance

24
Q

What is chronic diarrhoea?

A

Diarrhoea more than 6 weeks

Small bowel disease (eg. Coeliac, crohns)
Pancreatic disease (eg. Carcinoma, cystic fibrosis)
Colonic disease (eg. ulcerative colitis, crohns, carcinoma)

25
What is coeliac disease?
1:100 Mainly GI symptoms but other presentations Diagnose- serology tests, gastroscopy Dermatitis Herpetiformis (10%)- blisters (back, buttocks, elbows, knees)
26
How can you differentiate the cause of diarrhoea?
Small bowel/pancreatic- Pale, floating Throughout day Pain variable timing Pain not relieved by defaecation Colonic- Blood and mucus Morning Pain related to defaecation
27
What is the management of IBS?
Aminosalicylates Steroids Immunomodulatory therapy (eg. Methotrexate) TNF therapy (eg. Infliximab)
28
What are associated diseases of IBS?
Skin- erythema nodosum, pyoderma gangrenosum Mouth- ulcers Joints- ankylosing spondylitis Eyes- episcleritis, uveitis Vascular- thromboses Liver- corrhosis, CAH, primary sclerosing cholangitis
29
What are symptoms of colorectal cancer?
Asymptomatic (bowel cancer screening- FIT) Rectal bleeding Altered bowel habit Lethargy/weight loss
30
How is colorectal cancer managed?
Investigations- colonscopy, Barium enema, CT Tx= evaluate extent, limited to colon- surgical resection, advanced- chemo/radiotherapy
31
What are post hepatic causes of jaundice?
OBSTRUCTION OF BILE DUCTS/TRACTS, FAILURE TO INITIATE BILE FLOW (HEPATOCYTES) Gall stones- biliary colic, fever, fluctuating jaundice Eg. Choledocholithiasis Malignancy- constant pain radiating to back, weight loss Eg. Pancreatic carcinoma, cholangiocarcinoma Benign biliary stricture- fever, pain Eg. Post op, sclerosing cholangitis
32
What are hepatic causes of jaundice?
INABILITY OF LIVER TO CONVERT BILIRUBIN INTO BILE Infection- malaise, anorexia, pale stools, dark urine, RUQ discomfort Eg. Hep A, B, C, EBV Alcoholic hepatitis- similar symptoms to infection Drugs Eg. Augmentin, flucloxacillin Decompensated chronic liver disease- ascites, varices, hepatic encephalopathy Eg. Alcohol cirrhosis, Wilson’s disease, haemochromatosis
33
What are prehepatic causes of jaundice?
HAEMOLYSIS- ISOLATED RAISED BILIRUBIN LEVEL Haemolytic anaemia- anaemia, gall stones, splenomegaly, leg ulcers Eg. Sickle cell disease, hereditary spherocytosis
34
Signs of chronic liver disease?
Digital clubbing Palmar erythema Spider naevi Distended abdomen- ascites Complications- variceal bleeding