Gastrointestinal Flashcards
(187 cards)
Complications of GERD
- Esophagitis
- Stricture
- Barrett’s esophagus
- Esophageal adenocarcinoma
Esophageal squamous epithelium replaced by precancerous metaplastic columnar cells from the cardiac of the stomach
Barrett’s Esophagus
Atypical symptoms of GERD
Hoarseness Aspiration pneumonia "Asthma" Noncardiac chest pain Weight loss
Alarm symptoms of GERD
- Dysphagia
- Odynophagia
- Weight loss
- Bleeding (suspect malignancy)
Diagnosis of GERD
- Clinical diagnosis
- Endoscopy (used first)
- Esophageal manometry
- 24 hours ambulatory pH monitoring (gold standard)
Management of GERD
- Lifestyle modifications
- H2 blockers, PPIs, antacids
- Nissen fundoplication if refractory
Yellowing of the skin, nail beds, and sclera by tissue bilirubin deposition as a consequence of hyperbilirubinemia. Not a disease but a sign of a disease
Jaundice
Jaundice occurs when bilirubin is > _____
2.5 mg/dL
DDX for hematemesis
Esophageal varices Mallory-Weiss tear Esophageal neoplasms Gastritis Peptic ulcer disease Gastric carcinoma Caustic (corrosive) esophagitis Boerhaave syndrome
DDX for melena
Esophageal varices Gastritis Mallory-Weiss tear Peptic ulcer disease Gastric carcinoma
DDX for BRBPR
Hemorrhoids
Anal fissures
Intussusception
Colon CA
Most common cause of esophagitis
GERD
Risk factors for esophagitis
Pregnancy Smoking obesity EtOH use Chocolate Spicy foods Medications
Signs/Symptoms of esophagitis
- Odynophagia
- Dysphagia
- Retrosternal chest pain
Diagnosis of esophagitis
Endoscopy
Double-contrast esophagram
Management of esophagitis
Treat underlying cause
Most common causes of infectious esophagitis
Candida
HSV - small, deep ulcers
CMV - large superficial shallow ulcers
Allergic, inflammatory infiltration of the esophageal epithelium
Eosinophilic esophagitis
Eosinophilic esophagitis is most commonly associated with:
Atopic disease - food/non food allergies, asthma, eczema
Endoscopy of eosinophilic esophagitis will show:
Multiple corrugated rings on esophagus, +/- white exudates
How might esophinophilic esophagitis present in children?
Difficulty feeding or reflux
Most commonly due to prolonged pill contact with the esophagus, prolonged supination after pill ingestion
Pill-induced esophagitis
Pill-induced esophagitis is most commonly seen with:
- NSAIDs
- Bisphosphonates (-dronate)
- Potassium chloride
- Iron pills
- Vitamin C
- Beta blockers
- Calcium channel blockers
Management of pill-induced esophagitis
Take pills with at least 4 ounces of water, avoid recumbency for at least 30-60 minutes after pill ingestion