GASTROINTESTINAL DRUGS

Question 1

Prevent expulsion of stomach contents by decreasing stimulation of either the chemoreceptor trigger zone, near the medulla, or the vomiting center in the medulla

PREVENTS?

Answer 1

ANTI-EMETICS; Nausea/Vomiting

Question 2

Dramamine
Phenergan

Answer 2

Antihistamines

Question 3

Scopolamine

Answer 3

Anticholinergic

Question 4

Thorazine

Answer 4

Phenothiazines

Question 4

Granisetron Ondansetron

Answer 4

Serotonin receptor antagonist

Question 5

non-pharmacologic measures for nausea/vomiting

Answer 5

Dry toast, Tea, Crackers

Question 6

Store anti-emetics drug in____ & _____ container.

Answer 6

tight, light resistant

Question 7

Neutralize gastric acid

Answer 7

ANTACIDS

Question 8

Aluminum hydroxide,
Magnesium hydroxine
AlOH + MgOH (Maalox/Magaldrate)

are used for?

Answer 8

Peptic ulcers, reflux esophagitis, hiatal hernia

Question 9

Adverse reaction of aluminum compounds

Answer 9

Constipation

Question 10

Adverse reaction of Magnesium compounds

Answer 10

DIARRHEA

Question 11

ANTACIDS are administered with?

Answer 11

8 oz of glass water

Question 12

Recommended diet high in?

Answer 12

Calcium, Iron

Question 13

Inhibit secretion of pepsin
Block release of histamines

Answer 13

ANTI-PEPTIC ULCER DISEASE

Question 14

4 types of ANTI-PEPTIC ULCER DISEASE

Answer 14

1. Proton-pump Inhibitor (PPI)
2. H2-receptor Blockers
3. Cytoprotective agent
4. Anti-cholinergics

Question 15

Omeprazole
Lansoprazole

Answer 15

Proton-pump Inhibitor (PPI)

Question 16

Cimetidine
Ranitidine
Famotidine

Answer 16

H2-receptor Blockers

Question 17

Sucralfate
Misoprostol

Answer 17

Cytoprotective agent

Question 18

Chlordiazepoxide
Atropine sulfate

Answer 18

Anti-cholinergics

Question 19

Anti-peptic ulcer disease is used for management of

Answer 19

peptic ulcer disease, GERD; protects gastric mucosa from hydrochloric acid production

Question 20

Anti-peptic ulcer disease is given on

Answer 20

EMPTY STOMACH

Question 21

Avoid____ within 30 minutes of sucralfate

Answer 21

Antacids

Question 22

Avoid antacids within ____ hours of other anti-ulcer drugs

Answer 22

1-2

Question 23

Administer other drugs one to two hours after ____

Answer 23

Sucralfate

Question 24

MUST AVOID when taking ati-peptic ulcer disease

Answer 24

alcohol, spicy food and caffeinated beverages.

Question 25

full effect takes

Answer 25

2 weeks

Question 26

Forms the stool; Tx for diarrhea

Answer 26

ANTI-DIARRHEAL

Question 27

Kaolin and Pectin

Answer 27

Fluid absorbents (Decrease fluid content)

Question 28

Diphenoxylate hydrochloride Loperamide hydrochloride

Answer 28

Motility Suppressants (Decrease GI motility)

Question 29

Lactobacillus acidophilus

Answer 29

Enteric bacterium replacements

Question 30

CI for anti-diarrheal

Answer 30

Ulcerative colitis

Question 31

Motility suppressants may cause

Answer 31

physical dependence

Question 32

Agents which facilitate defecation, and treat constipation + Increase bulk within the bowel + Lubricate the intestinal walls + Increase peristalsis

Answer 32

LAXATIVES

Question 33

Mineral oil Colace Metamucil Dulcolax Milk of magnesia TREATS?

Answer 33

Constipation

Question 34

Intestinal lubricants inhibit absorption of

Answer 34

fat soluble vitamins

Question 35

fat soluble vitamins like ____ (excrete excessive loss of water) which may cause

Answer 35

Saline cathartics; dehydration, hypernatremia

Question 36

To treat constipation, diet must include

Answer 36

High fiber, fluid intake