Gastrointestinal System Flashcards

(75 cards)

0
Q

secretion (n.)

A

release of enzymes, hydrochloric acid, and hormones to aid in digestion

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1
Q

What are the four processes of the GI tract?

A

Digestion, secretion, absorption, and motility

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2
Q

motility (n.)

A

smooth muscle contraction that is necessary to move materials through stomach and intestines

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3
Q

digestion (n.)

A

breakdown and dissolving of large particles into small particles that can be absorbed

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4
Q

absorption (n.)

A

transport of small particles across the epithelial layer of intestine into blood or lymph

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5
Q

What are the three pancreatic enzymes that break peptide bonds in proteins?

A

Trypsin, chymotrypsin, and elastase

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6
Q

What is the function of carboxypeptidase?

A

Splits off terminal amino acid from carboxyl end of protein

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7
Q

What is the function of amylase?

A

Splits polysaccharides into glucose and maltose

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8
Q

What are the three disaccharides?

A

Sucrose, lactose, and maltose

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9
Q

What two molecules make up sucrose?

A

Glucose and fructose

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10
Q

What two molecules make up lactose?

A

Glucose and galactose

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11
Q

What two molecules make up maltose?

A

Two glucose molecules

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12
Q

What is the internal environment?

A

Blood and plasma (interstitial fluid)

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13
Q

What is the name of the membrane of intestinal epithelial cells facing the lumen of the intestine?

A

Luminal (brush border) membrane

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14
Q

What is the name of the membrane between intestinal epithelial cells and interstitial fluid (capillaries)?

A

Basolateral membrane

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15
Q

What is the inactive form of pepsin?

A

Pepsinogen

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16
Q

What cells release pepsinogen?

A

Chief cells

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17
Q

What do parietal cells release?

A

HCl and intrinsic factor

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18
Q

What converts pepsinogen into pepsin?

A

Hydrochloric acid

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19
Q

What two substances first emulsify fat droplets?

A

Bile salts and phospholipids

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20
Q

What do bile salts and phospholipids emulsify fat droplets into?

A

Emulsion droplets

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21
Q

What substances breakdown emulsion droplets?

A

Bile salts and pancreatic lipase

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22
Q

What are emulsion droplets further emulsified into?

A

Micelles

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23
Q

Why are fat droplets broken down so much only to be partial reformed?

A

To allow for rapid diffusion into epithelial cells

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24
Fatty acids are added to triglycerides inside epithelial cells, packaged as _______, and are secreted into the blood.
chylomicrons
25
What cellular structure adds fatty acids to triglycerides inside epithelial cells of villi?
Smooth endoplasmic reticulum
26
What activates trypsinogen?
Membrane-bound enterokinase
27
What is the activated form of trypsinogen?
Trypsin
28
What's the volume of the stomach when empty?
50 mL
29
What is the volume of the stomach when full?
1.5 L
30
What's the rate of peristaltic waves in the stomach?
~3 waves/min
31
What small intestine structure prevents retrograde movement of material into the stomach?
Pyloric valve
32
Where is gastrin produced?
Antrum of the stomach
33
Where is CCK produced?
Small intestine
34
Where is secretin produced?
Small intestine
35
What are the stimuli for gastrin release?
Amino acids and peptides in the stomach; parasympathetic nerves
36
What is the stimulus for CCK release?
Amino acids and fatty acids in small intestine
37
What is the stimulus for secretin release?
Acid in the small intestine
38
What are the factors inhibiting gastrin release?
Acid in the stomach; somatostatin
39
Which hormones stimulate acid secretion in the stomach?
Gastrin
40
Which hormones inhibit acid secretion in the stomach?
CCK and secretin
41
What effect does gastrin have on stomach acid secretion?
Stimulatory
42
What effect does CCK have on stomach acid secretion?
Inhibitory
43
What effect does secretin have on stomach acid secretion?
Inhibitory
44
Which hormones stimulate stomach motility?
Gastrin
45
Which hormones inhibit stomach motility?
CCK and secretin
46
What effect does gastrin have on stomach motility?
Stimulatory
47
What effect does CCK have on stomach motility?
Inhibitory
48
What effect does secretin have on stomach motility?
Inhibitory
49
Which hormone stimulates stomach growth?
Gastrin
50
What effect does gastrin have on stomach growth?
Stimulatory
51
What effect does CCK have on bicarbonate secretion in the pancreas?
Potentiates secretin's actions
52
What effect does secretin have on bicarbonate secretion in the pancreas?
Stimulatory
53
What effect does CCK have on enzyme secretion in the pancreas?
Stimulatory
54
What effect does secretin have on enzyme secretion in the pancreas?
Potentiates CCK's action
55
Which hormones stimulate growth of the exocrine pancreas?
Gastrin, CCK, and secretin
56
What affect does CCK have on bicarbonate secretion in the liver?
Potentiates secretin's action
57
What effect does secretin have on bicarbonate secretion in the liver?
Stimulatory
58
Which hormone stimulates gallbladder contraction?
CCK
59
Which organs secret bicarbonate?
Pancreas and liver
60
What pancreatic enzyme digests triglycerides into free fatty acids and a monoglyceride?
Lipase
61
The enteric nerves in the GI wall synapse with other autonomic neurons. (T/F)
True
62
Glucose is transported across the basolateral membrane of the small intestine by facilitated diffusion. (T/F)
True.
63
What enzymes break down carbohydrates/starch?
Salivary amylase, pancreatic amylase, and brush border enzymes
64
What monomer are carbohydrates/starches broken down into?
Monosaccharides
65
Where are monosaccharides absorbed?
Luminal epithelial membrane of small intestine
66
What are the three monosaccharides?
Glucose, fructose, and galactose
67
What two enzymes begin protein digestion?
HCl and pepsin
68
What proteases are created in the pancreas?
Trypsin, chymotrypsin, and carboxypeptidase
69
What protease is secreted by small intestine glands?
Aminopeptidase
70
What is the inactive form of trypsin, and what activates it?
Trypsinogen, activated by membrane-bound enterokinase (enteropeptidase)
71
What is the inactive form of chymotrypsin?
Chymotrypsinogen
72
What is the inactive form of carboxypeptidase, and what activates it?
Procarboxypeptidase, activated by membrane-bound enterokinase (enteropeptidase)
73
What are the layers of the GI tract?
Mucosa, submucosa, muscularis externa, and serosa
75
What layers make up the mucosa?
Epithelium, lamina propria, and muscularis mucosa