Gastrointestinal System Flashcards

1
Q

What are the functions of the digestive tract?

A
  • Transport
  • Digest intake
  • Absorb nutrients
  • Excretion
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2
Q

What is the general structure of the digestive tract?

A
  • Mucosa (inner lining)
  • Submucosa (Meissner’s Plexus)
  • Muscle (Auerbach/Myenteric Plexus)
  • Serosa
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3
Q

What is the Meissner’s Plexus made up of?

A

Blood vessels
Glands
Nerve tissue

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4
Q

What is the nerve layer in the muscle of the digestive tract?

A

Auerbach/Myenteric Plexus

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5
Q

What is the type of nervous system in the digestive tract?

A

Enteric nervous system

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6
Q

What are the THREE phases of swallowing?

A
  1. Oral (voluntary)
  2. Pharyngeal (reflex)
  3. Oesophageal (reflex)
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7
Q

How long is the oesophagus and what type of cells does it have?

A

25cm long with squamous cells

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8
Q

What is Peristalsis?

A

Wave of muscle contraction

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9
Q

What are the top, middle and bottom parts of the stomach?

A

Top: Fundus
Middle: Body
Bottom: Antrum

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10
Q

What are the FIVE cell types in the stomach?

A
  1. Goblet
  2. Parietal
  3. ECL
  4. Chief cells
  5. Hormone secreting
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11
Q

Name the Gastric Acid Secretagogues

A
  • Histamine
  • Acetylcholine
  • Gastrin
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12
Q

How long is the small intestine and what are the THREE parts of it?

A

5m long
Duodenum (12in)
Jejunum
Ileum

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13
Q

What is the structure of the mucosa in the small intestine?

A

Folded in microvilli

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14
Q

What are interstitial cells of Cajal?

A

Pacemaker cells that moves chyme towards the colon in peristalsis

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15
Q

Where is bile stored and where does it empty into?

A

Stored in the gallbladder
Emptied into the duodenum

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16
Q

Are digestion and absorption regulated?

A

No
Motility and secretions are by hormones and neural mechanisms

17
Q

Name some glands in intestinal mucosa?

A
  • Paracrine
  • Autocrine
  • Endocrine
18
Q

What does Meissner’s Plexus control?

19
Q

What does Auerbach/Myenteric Plexus control?

A

Muscle layers

20
Q

What does Parasympathetic nerves do to digestive activity?

A

Increases digestive activity

21
Q

What are the THREE phases in the regulation of gastric function (acid secretion)?

A
  1. Cephalic
  2. Gastric
  3. Intestinal
22
Q

What stimulates the CEPHALIC phase release?

A

Sight
Smell
Food taste
Reflex

23
Q

How is the CEPHALIC phase mediated?

A

By vagus stimulating parietal cells

24
Q

What stimulates GASTRIC phase release?

A

Distension of stomach
Presence of food

25
How does GASTRIC release phase regulate itself?
Self regulation by negative feedback
26
What stimulates INTESTINAL phase inhibition?
Chyme in duodenum
27
What does the inhibition of gastric acid release?
Secretin
28
Name TWO proteins that inhibit parietal cells
1. CCK 2. GIP
29
How are intestinal functions regulated?
Neural regulation by enteric nervous system
30
What are the THREE reflexes linked with intestine function regulation?
1. Gastroileal 2. Illeogastric 3. Intestino-intestinal
31
What proteins increase pancreatic and liver bile secretions?
CCK and Secretin
32
Where does digestion begin?
Mouth
33
What is the function of pancreatic amylase?
Digests carbohydrates in duodenum
34
Name some intestinal enzymes
Maltase Sucrase Lactase
35
What are the only digestible sugars?
Glucose Galactose Fructose
36
What is the function of pepsin in the stomach?
Convert proteins into short chain amino acids for absorption
37
What is the function of bile salts?
Emulsify droplets of triglycerides
38
Where do enzymes from the pancreas attach to bile?
To the head of bile which is fat soluble