Gatfield

Question 1

NTF2

Answer 1

Ran GDP importateur, séparés par l’action de Ran GEF

Question 2

NLS

Answer 2

basique / Arginine R, Lysine k

Question 3

NES

Answer 3

hydrophobe, Leucine L , Isoleucine I, Valine V, F, M

Question 4

euchromatine

Answer 4

décondensé 11nm

Question 5

hétérochromatine

Answer 5

condensé 30-120nm

Question 6

LMNA

Answer 6

lamines A, A delta 10, C, C2

Question 7

LMNB1

Answer 7

lamine B1

Question 8

LMNB2

Answer 8

lamines B2, B3

Question 9

ribosomes

Answer 9

28S, 5.8S, 5S -> grosse
18S -> petite

Question 10

cyclines

Answer 10

6 → 3 cyclines D (G1), cycline E (G1/S), cycline A (S), cycline B (M)

Question 11

Cdk

Answer 11

Cyckine dependant kinase → 4

Question 12

CAK

Answer 12

kinase d’activation de la Cdk → phosphate activateur ( boucle T)

Question 13

Wee1

Answer 13

kinase, phosphate inhibiteur (M-Cdk)

Question 14

Cdc25

Answer 14

phosphatase , enlève phosphate inhibiteur (M-Cdk)

Question 15

CKI

Answer 15

cycline dependant kinase inhibitor → p16, p21, p27

Question 16

CKI p16

Answer 16

environnement défavorable → inhibition cycline D G1

Question 17

p53

Answer 17

si ADN endommagé (pas par réplication) → p53 → CKI p21

Question 18

ADN endommagé ou non-réplique G2/M → M-Cdk

Answer 18

CKI p21 ou Wee1

Question 19

Prophase I

Answer 19

leptotène, zygotène, pachytène, diplotène, diacinèse

Question 20

Spo11

Answer 20

endonucléase → coupure sur les deux brins → attire complexe de recombinaison (pachytène)