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N352 > Gender > Flashcards

Gender Flashcards

1
Q

What are the goals of gender affirming hormone therapy?

A

Modify the secondary sex characteristics of the body

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2
Q

What is the MOA of GnRH analogues?

A

Suppress gonadotropin releasing hormone

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3
Q

Route of GnRH analogies

A

Injectable
Implant

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4
Q

Side effects of GnRH analogies

A

Prevents natural gonadal development/fertility while in use

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5
Q

What drugs is a GnRH analogies?

A

Lupron

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6
Q

Goals of trans-masculine hormone therapy

A

Muscular development
Fat redistribution
Deepening of voice
Body and facial hair growth

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7
Q

Areas not affected in trans-masculine hormone therapy

A

Existing breast tissues
Physical size/bone structure

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8
Q

Side effects of trans-masculine hormone therapy

A

Fertility suppression
Mood changes

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9
Q

MOA of testosterone

A

Synthetic testosterone replacement

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10
Q

Testosterone routes of administration

A

Topical
Injectable
Transdermal

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11
Q

Side effects of testosterone

A

Increases risk of heart disease and diabetes to that of cis men
Increases red blood cell counts
Birth defects
Liver damage
Hair loss

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12
Q

MOA of finasteride

A

Blocks production of DHT responsible for terminal hair loss

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13
Q

Finasteride route of administration

A

Oral

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14
Q

Side effects of finasteride

A

Decrease prostate-specific antigen
Effect on sexual function

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15
Q

What medications are progestin contraceptions?

A

Norethindrone
Medroxyprogesterone

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16
Q

MOA of progestin contraception

A

Synthetic progestin compounds use negative feedback to halt ovulation cycle

17
Q

Patient education for progestin contraception

A

Must be taken at the same time each day, otherwise spotting can occur
Cycle cessation can take 2-3 months
Testosterone alone can’t prevent pregnancy

18
Q

Permanent changes induced by testosterone

A

Bigger clitoris
Deeper voice
Gradual growth of mustache and beard
Hair loss at temples and crown of head
Thick, coarse hair on abdomen, arms, back, chest, and legs

19
Q

Not permanent changes induced by testosterone

A

Acne
Menstrual stopping
More abdominal fat - changing from pear to apple shape
More muscle mass and strength
More sex drive
Vaginal dryness

20
Q

Goals of trans-feminine hormone therapy

A

Breast development
Fat redistribution
Skin and hair changes
Mood changes
Decrease/cessation of hair loss

21
Q

Side effects of trans-feminine hormone therapy

A

Change/decrease in libido or sexual function
Fertility suppression

22
Q

Areas not effected by trans-feminine hormone therapy

A

Voice
Facial hair follicles
Physical size/bone structure

23
Q

MOA of estrogen

A

Synthetic estrogen replacement

24
Q

Estrogen routes of administration

A

Oral or sublingual
Transdermal
SQ or IM

25
Q

Side effects of estrogen

A

Liver damage
Increased risk of breast cancer to that of cis women
Increased risk of VTE

26
Q

Permanent changes induced by estrogen

A

Breast development

27
Q

Non permanent changes induced by estrogen

A

Slow in growth/changes in body hair
Less fat on abdomen and more on buttocks - apple shape to pear shape
Male pattern baldness cessation
Softer skin
Loss of strength/muscle mass and tone
Fertility suppression
Decrease or change in libido
Changes in mood

28
Q

MOA of spironolactone

A

Aldosterone antagonist
Has anti-androgenic effects at higher doses

29
Q

Spironolactone routeofadministration

A

Oral

30
Q

Side effects of spironolactone

A

Dehydration
Frequent urination
Gynecomastia
Reduction in male fertility
Possible serum electrolyte imbalances - low sodium high potassium

31
Q

Bicalutamide MOA

A

Testosterone blocker
Medication binds to testosterone tissue receptors

32
Q

Bicalutamide routes of administration

A

Oral

33
Q

Side effects of bicalutamide

A

Liver toxicity
Reduction in fertility and erectile ability

34
Q

Which medications are progesterone?

A

Micronized progesterone
Medroxyprogesterone

35
Q

MOA of progesterone

A

Synthetic progesterone replacement for libido or breast development

36
Q

Progesterone routes of administration

A

Oral
Topical

N352 (4 decks)

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