Gene Basic Flashcards
(26 cards)
What is gene therapy?
A technique that modifies genes to treat or prevent disease.
True or False: Gene therapy can only be used to treat genetic disorders.
False
Fill in the blank: Gene therapy involves the introduction, removal, or alteration of ________ within a person’s cells.
genes
What are the two main types of gene therapy?
Somatic gene therapy and germline gene therapy.
Multiple Choice: Which of the following is a common method of delivering genes in gene therapy? A) CRISPR B) Antibiotics C) Vaccines
A) CRISPR
What is somatic gene therapy?
A type of gene therapy that targets non-reproductive cells.
True or False: Germline gene therapy alters the genes in sperm or eggs.
True
What is the primary goal of gene therapy?
To correct or compensate for defective genes.
Fill in the blank: The first successful gene therapy was performed in ________.
1990
What are vectors in gene therapy?
Vehicles used to deliver therapeutic genes into target cells.
Multiple Choice: Which vector is commonly used in gene therapy? A) Adenovirus B) Bacteria C) Yeast
A) Adenovirus
What is a potential risk associated with gene therapy?
Unintended immune response or insertional mutagenesis.
True or False: Gene therapy can provide a permanent cure for genetic disorders.
True
What does the term ‘in vivo’ mean in the context of gene therapy?
Gene therapy performed directly within the living body.
Fill in the blank: The ethical concerns of gene therapy often revolve around ________ gene editing.
germline
What is the role of CRISPR in gene therapy?
To edit genes with high precision.
Multiple Choice: Which of the following is NOT a gene therapy technique? A) Gene editing B) Gene silencing C) Gene cloning
C) Gene cloning
What is the significance of the FDA in gene therapy?
It regulates and approves gene therapy products for safety and efficacy.
True or False: Gene therapy is only available for rare diseases.
False
What does ‘ex vivo’ refer to in gene therapy?
Gene therapy performed on cells outside the body before reintroducing them.
Fill in the blank: The first gene therapy approved by the FDA was for ________.
leukemia
What is a major challenge in gene therapy?
Ensuring the effective delivery of genes to the right cells.
Multiple Choice: Which condition has been treated with gene therapy? A) Cystic fibrosis B) Diabetes C) Hypertension
A) Cystic fibrosis
What is the role of regulatory agencies in gene therapy?
To ensure safety, efficacy, and ethical compliance of gene therapy trials.
