Gene Expression Flashcards

1
Q

Anticodon

A

Three consecutive bases on the tRNA

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2
Q

Codon

A

Three consecutive bases on the mRNA

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3
Q

Deletion mutation

A

A mutation on the DNA where a base(s) is removed, resulting in a frame shift

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4
Q

DNA

A

Deoxyribose nucleic acid, A joins with T, C joins with G. Double stranded, helix shaped large molecule, a whole chromosome. Deoxyribose sugar

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5
Q

Enzyme

A

A folded protein which acts as a biological catalyst to speed up the rate of a chemical reaction in an organism

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6
Q

Frameshift

A

Change in bases that the ribosome reads

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7
Q

Gene

A

A piece of DNA which codes for the making of a protein / feature

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8
Q

Gene expression

A

The process where the instructions on our DNA are converted into a functional protein, includes transcription, translation and protein folding

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9
Q

Genotype

A

The genetic make-up of an organism for a feature

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10
Q

Insertion mutation

A

A mutation on the DNA where a base(s) is added resulting in a frame shift

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11
Q

Metabolic pathway

A

A series of enzyme-controlled reactions, where the product of one reaction becomes the substrate of the next

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12
Q

Missense mutation

A

A change of the base on the DNA which codes for a different amino acid. This may or may not alter the shape of the protein and therefore it’s function

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13
Q

mRNA

A

Messenger RNA. Made during transcription in the nucleus. Carries the instructions to the ribosome to make a polypeptide chain. Contains codons

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14
Q

Mutagen

A

Environmental factor which causes the mutation e.g. agent orange, x-rays etc

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15
Q

Mutation

A

A permanent change in the bases on the DNA

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16
Q

Non-sense mutation

A

A change of the base on the DNA which changes the instructions, so a STOP codon occurs in the wrong place. Protein is greatly affected

17
Q

Peptide bond

A

Bond formed between 2 amino acids during translation

18
Q

Phenotype

A

The physical appearance of a feature

19
Q

Point mutation

A

A change of only one or a few bases on the DNA

20
Q

Protein

A

A substance made of many amino acids joined together to form a polypeptide chain, which gets folded into a functional protein (enzymes are a type of protein)

21
Q

Redundancy

A

The fact that multiple codons code for the same amino acid, e.g. CCU, CCC, CCA and CCG all code for the amino acid Pro

22
Q

RNA

A

Ribonucleic acid. A bonds with U and G bonds with C. Three types, tRNA, mRNA and rRNA. Single stranded and shorter than DNA. Sugar is ribose

23
Q

Same-sense mutation

A

A change of the base on the DNA where the bases still code for the same amino acid. This is due to the redundancy of the genetic code

24
Q

Silent mutation

A

A mutation that is neither favourable nor harmful, that remains in a population

25
Q

Start codon

A

The start signals on the mRNA which initiates translation. Always AUG

26
Q

Stop codon

A

These 3 codons on the mRNA (UAA, UAG, UGA) do not code for an amino acid therefore telling the ribosome where to stop translation

27
Q

Substitution mutation

A

A mutation where the base(s) on the DNA are swapped

28
Q

Transcription

A

The process by which DNA going to mRNA, occurs in the nucleus. Controlled by RNA polymerase

29
Q

Translation

A

The process by which mRNA going to polypeptide chain, occurs in the cytoplasm on the ribosome

30
Q

Triplet

A

Three consecutive bases on the DNA

31
Q

tRNA

A

Transfer RNA. Carries an amino acid to the ribosome. 3 bases on the mRNA = an anti codon