gene expression Flashcards
(11 cards)
when does gene expression happen
any time from dna to protein stage
what turns on and off gene expression
transcription factors: : promoters, enhancers, and silencers
three steps of eukaryotic transcription
initiation, elongation, termination
how does transcription initate + why happens if it doesn’t
it has to bind to the promoter region, if not, the gene expression is stopped
what are spliced in post transcriptional regulation
splicing removes introns (non-coding) and joins the exons (protein-coding)
translational regulation
if microRNA bind to specific mRNA sequence, it blocks translation
post-translational regulation
proteins changed by adding chemical groups (ie. phosphorylation and acelytation) changes gene expression
transcriptional regulaton
adding methylation ?
how is a gene turned off/on
when a repressor (protein) binds to a silencer
epigenetic changes with age
why doesn’t epigenetic modifications affect nitrogenous bases
bc it does not alter the dna but only when gene binds to DNA methylation.
