Gene Interaction Flashcards
What is gene interaction
When more than one nonallelic gene influence outcome of single trait
Type of gene interaction
Epistasis- gene(epistasis) mask expression of other gene(hypostasis)
Interaction between allele of different locus
-non allelic interaction (vvv imp)
Dominance vs epistasis
Dominanace- interaction between diff alleles of same gene
Epistasis- interaction between different genes
Types of epistasis with ration and example
Original 9:3:3:1
Duplicate recessive -9:7
aa epistatic to B/b
bb epistatic to A/a
Mutation on one gene
Eg lathyrus odoratus(flower colour of sweet pea)- 🟣 🤍
Both A and B req for anthocyanin production
Duplicate dominant - 15:1
A epistatic to B/b
B epistatic to A/a
Wheat kernel colour
Dominant and recessive- 13:3
B epistatic to A/a
When dominant allele of one gene supress dominant allele of second gene
PRIMULA PLANT- MALVIDIN 🔵 plant
B supress production of malvidin so 🤍
Recessive- 9:3:4
aa epistatic to B/b
Recessive allele at one gene mask/reduce other gene
AGOUTI COAT COLOUR- black and albino
A black
B AGOUTI
bb black
aa- albino (doesn’t depend on b/B)
Dominant-12:3:1
A epistatic to b/B
Dominant allele mask expression of of allele of second gene
A- a express
If aa, B/b express
SQUASH COLOUR- 🤍 💛 💚
A white
b green
B yellow
Complement analysis
K/as cis trans test.
Determine whether 2 independently isolated mutants with the same phenotype have mutation in same/different genes
Cross mutant strain
If mutation in different gene- progeny wild (complement each other)
If mutation in same gene at diff location- mutant
Pleiotropy
Effect of one gene on more than one phenotype
White eyes in drosophila also effects shape of organs in female and sperm storage
Frizzle trait in chicken- defective fether and metabolism rate nd temp sensitivity etc
Sickle cell anemia
Polygenic trait
Many genes controlling single trait
