General Flashcards
(591 cards)
Which tumours are associated with adrenal metastasis?
Lung and breast
Adrenaline vs Noradrenaline
Adrenaline Alpha and Beta Noradrenaline predominantly alpha Alpha - peripheral vasoconstriction Beta - cardiac chronotropic and inotropic
What is dopexamine
Splanchnic vasodilator
Scaly, thick and greasy appearance.
Keratin plugs
Seborrhoeic Keratoses
Name 4 clinical features of a mass/swelling that make it suspicious of being a sarcoma
> 5cm soft tissue mass
Deep / Intramuscular Location
Rapidly Growing
Painful
Ewings vs Osteosarcoma
Ewings is a diaphyseal, small round tumour.
Radiologically - Onion Skin appearance- represneting lysis with periosteal elevation.
Osteosarcoma is usually a tumour of the metaphysis (osteoblastic cell origin)
Radiologically - sunburst appearance = sclerotic destruction
Discuss Anterior Interosseus Nerve
Topography
Innervation
Topography:
Branch of the emdian nerve —> travels along anterior interossues membrane of the forear between flexor pollicus longus and flexor digitorum profondus ending at pronator quadratus
Innervates:
Flexor Pollicis Longus
Pronator Quadratus
Radial Half - FDP
Anion Gap
Calc
Causes
Calculation (Na+K+)-(Cl+HCO3)
Normal 10-18
Low Anion Gap
hypoalbuminaemia, increased cations (MG++, Ca++, IgG),
Normal Anion Gap - Hyperchloraemic
Bicarb Loss, Renal Tubular Acidosis (moreso in type II), Drugs (Acetozolamide), Chloride Injection, Addison’s Disease (Type IV RTA)
High Anion Gap
Lactate, Ketoacidosis, Urate, Exogenous Acids
Causes of delayed gastric emptying
Neuronal:
Vagotomy, Diabetic Gastroparesis (Vagal Nerve Disruption)
External Compression:
Pancreatic masses abutt the duodenum thereby delaying ewmptying,
Internal Obstruction:
Distal Gastric Malignancies, Pyloric Stenosis
Ileostomy
Location
Construction
Complications
Location: Triangle between ASIS, Umbilicus and symphysis pubis.
Construction: 2cm incision, stoma length 2.5 cm, spouted, one third between umbilicus and ASIS.
Complications: Dermatitis, necrosis, prolapse, retraction, high output
Normal stoma output: 5-10 ml/kg/24 hour period. If >20 ml/kg/24 hour period —> IV fluids and supplementation
Vagina lymph vessel drainage:
Superior
Inferior
Superior - drain into the internal + external iliac nodes
Inferior - drain into the superficial inguinal nodes
Contents of jugular foramen
Bones forming jugular foramen
Bones: Posterior Occipital bone + Petrous portion of temporal bone
Contents - CN IX, X, XI. Inferior Petrosal Sinus, Sigmoid Sinus, Meningieal arteries (from occipital and ascending pharyngeal artery)
Contents of Superior Orbital Fissure
CN III, IV, VI
Recurrent meningeal artery
Superior Opthalmic Vein
V1 - Lacrimal, Frontal and Nasociliary
What do each of these secrete:
Parietal Cells
Chief Cells
Surface Mucosal Cells
Parietal Cells - HCl, Ca, Na, Mg, IF
Chief Cells - Pepsinogen
Surface Mucosal Cells - Mucus and Bicarbonate
Dep Peroneal nerve
Course
Action
What (sometimes) atraumatic condition can it become compromised in?
L4-S2
Branch of common peroneal nerve at lateral aspect of fibula. Travels in anterior leg comparment. passes ankle anteriorly between two malleoli where it bifurcates:
Pre - Bifurcation: - Tibialis anterior, enxtensor hallucis longus, extensor digitorum longus, peroneus tertius
Lateral - Branch supplies extensor hallucis brevis and extensor digitorum brevis
Medial - cutaneous branch innervating skin at the webspace between 1st and 2nd digits
Acts to - evert foot, dorsiflex ankle and extend toes
It can become compromised in compartment syndrome of the anterior compartment
Berry’s Sign
Absence of carotid pulse due to thyromegaly
Thyroid Malignancy:
Psammoma Bodies
Skull Metastases
Elderly females
Pappilary - Psammoma Bodies. Picked up via FNA
Lymphatic spread
Follicular - Not well picked by FNA –> need hemithyroidectomy. Haematogenous spread (bones)
Anaplastic - Elderly females. Poor prognosis. palliative debulking
Otosclerosis
Patho
Treatment
Fixation of stapes to oval window
Treatment involes stapedectomy + prosthesis insertion
Pethidine caution in…
Renal patients
It has a toxic metabolite which accumulates in renal dysfunction —> Muscle twitching and convulsions
Pharyngeal Pouch
True diverticulum (Zenker’s)
Involves all layers of mucosa.
Posteromedial herniation between thyropharyngeus and cricopharyngeus
Discomfort after eating - think..
Chronic Mesenteric Ischaemia
Mesenteric Vascular Disease
Acute Mesenteric Ischaemia - Embolic. Sudden onset pain, vomiting and diarrhoea
Acute on chronic - Post-prandial discomfort –> Acute
Mesenteric Venous Thrombosis –> Picture of weeks. Symptoms present when arterial inflow is compromised
Low flow mesenteric infarction –> inotrope use, intercurrent cardiovascular compromise
Describe rectus sheath
Above costal margin –> Aponeurosis of external oblique aponeurosis
Between costal margin and arcuate line –> Anterior rectus sheath - External oblique aponeurosis + anterior internal oblique aponeurosis. Posterior rectus sheath- Posterior internal oblique aponeurosis + Transversus abdominus
Below arcuate line –> There is no posterior rectus sheath. External and internal oblique aponeurosis alongside transversus abdominus form anterior rectus sheath. posterior to this is transversalis fascia then peritoneum.
Arcuate line is 1/2 between umbilicus and pubic crest






