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Flashcards in General Anesthetics Deck (3)
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1
Q
  • 5 Stages?
  • Potency =? (2)
  • Balanced: Sedative? Analgesics? Anti musc?
  • 2 factors that influence onset? High B:G? (2) Low?
  • Depth =? Order of filling? (3)
  • IV adjucvtvants: Etomidate (GA)? Ketamine (Dissoc.)? Midazolam (BDZ)? Propofol (GA)? Fentanyl (opoid)? Thiopental (GA)?
A
  • analgesia, delerium, surgical, no surgery, medullary paralysis
  • Lipid sol., 1/ MAC
  • BDZ; opioid/ LA; glycopyrolate
  • Conc., and Low B:G; Halothane/methoxyflurane; N2O
  • Conc. of anesthetic in brain; Brain, Muscle, Fat
  • Rapid onset; CV stim for increased CBF; Amnesia; Induction/ anti emetic; analgesia; fast onset
2
Q
  • GA’s act on? (3)
  • 2 first GA? Next flammable? Then?
  • 3 potent GA’s?
  • MOA: 2 hypotheses?
  • Ideal characteristics? (3)
  • Progression of anesthetic? Order? (8)
  • What is often used for fast onset stage 1 to 3?
A
  • GABA/ Ca and K at higher concentrations
  • NO, diethyl ether; cyclopropane; Halothane
  • Methoxyflurane/Halothane/Chloroform
  • Lipid due to potency being related to oil:gas; protein act via hydrophobic pockets in membrane proteins
  • Rapid/smooth onset; rapid recovery; wide safety margin
  • Descending depression: Fine motor, altered consc/analges, loss of temp reg, uncosciuss., eye stuff, muscle tone, resp. failure, CVD, coma
  • Thiopental
3
Q
  • Uptake elimination icnrease with? (5)
  • Volatile vs. IV GA?
  • 3 rules of breathing in high volume gas?
A
  • higher conc., Higher AVR, Less PBF, Lower Blood:Gas, High potency
  • IV known MOA on NT release
    1. ) Conc. effect: Lose O2 out of lungs with gas in
    2. ) 2nd gas: When breathing 2 gas; increase intake of second drug higher than normal
    3. ) Diffusion hypoxia: When stop intake, alveoli fill with gas and O2 dillutes out