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Leeds MBCHB Year 4 GOSH > General Gynae > Flashcards

General Gynae Flashcards

(71 cards)

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1
Q

PMS management for: mild, moderate and severe symptoms

A

Mild: lifestyle (complex carbs)
Moderate: COOP
Severe: sertraline

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2
Q

3 red flags for menorrhagia that would indicate TV USS

A

IMB, postcoital bleeding, pelvic pain/ discomfort

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3
Q

All women with menorrhagia require

A

FBC

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4
Q

First line treatment in women with menorrhagia that do not need contraception

A

TXA/ mefenamic acid

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5
Q

First, second and third line treatment in women with menorrhagia that need contraception

A

1: IUS
2: COOP
3: long acting progesterone (DEPO)

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6
Q

Mullerian agenesis presentation

A

Teenagers presenting with amenorrhoea and no pain

From lack of uterus

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7
Q

Clomifine

A

Anti-oestrogen used to treat fertility issues in PCOS

Metformin second line

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8
Q

What do women with PCOS undergoing IVF, are particularly at risk of it:

A

Ovarian hyperstimulation syndorme

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9
Q

Common pattern of endometriosis pain

A

With period/ cyclical

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10
Q

First line investigation in infertile women after 1 year

A

Day 21 progesterone

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11
Q

CA125 used to measure

A

Ovarian cancer

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12
Q

3 components to risk malignancy index and for what cancer

A

Ovarian

Ca125, US findings, menopausal status

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13
Q

How long after termination will HCG test be positive

A

Upto 4 weeks

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14
Q

In molar pregnancy high levels of HCG can imitate what hormone

A

TSH

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15
Q

Management for all cases of secondary dysmenorrhoea

A

Referral to gynaecologist

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16
Q

Management of ectopic pregnancy with heart beat

A

Surgical

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17
Q

Turners syndrome chromosomes

A

45X

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18
Q

Cord prolapse management

A

Hand into vagina to elevate the presenting part

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19
Q

Treatment given to all HIV patients with CD4 < 200 to prevent ?

A

Pneumocystis jirovceii pneumonia

Co-trimoxazole (septrin)

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20
Q

Changes to smear testing in women with HIV

A

Every year as high risk HPV

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21
Q

When is zidovudine used in labour

A

C section in women with viral load >10000 (very high)

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22
Q

Drug given to children of HIV mother

A

Zidovudine for 4 weeks if low viral load

Zidovudine, lamivudine and nevirapine for 4 weeks if high viral load

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23
Q

Can HIV be passed on in breast feeding

A

Yes - even if undetectable

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24
Q

What is Fitz Hugh Curtis syndrome

A

Complication of PID

Inflammation and infection of liver cavity causing adhesions

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25
Hypermesis gravidarum diagnostic criteria
5% weight loss Dehydration Electrolyte imbalance
26
First line pregnancy anti-emetic
Prochlorperazine | Ginger and acupressure on PC6 wrist
27
FSH levels in menopause
Very high (>40)
28
How to determine if pregnancy of unknown location is viable
Monitor HCG over 48 hours. Should double. (>63% acceptable) Ectopic will be less
29
Medical management of pregnancy termination drug
Methotrexate (cannot conceive for a further 3 months)
30
Missed miscarriage
Fetus no longer alive - no symptoms
31
Threatened miscarriage
Vaginal bleeding, CLOSED CERVIX, fetus alive
32
Inevitable miscarriage
Vaginal bleeding, OPEN CERVIX
33
Investigation to diagnose miscarriage
TV USS
34
Difference between triple and quad testing for Downs
Quad includes Inhibin A which makes it slightly more sensitive
35
Low AFP likely to indicate
Downs
36
AFP, estriol and HCG readings in Downs
AFP low Estriol low HCG high
37
AFP, estriol and HCG readings in Edwards
All low | HCG high in Downs
38
Edwards karyotype
trisomy 18
39
Can COOP be prescribed while breast feeding
UKMEC 4 up to 6 weeks the UKMEC 2
40
SSRI choice in pregnancy
Sertraline
41
1st and 2nd line mx of endometriosis
Paracetamol/ NSAIDS COOP 3: POP/ depo/ implant 4: GnRH analogues
42
Methotrexate use before pregnancy - management
MAN AND WOMEN must stop using it 6 months before
43
Rokitansky's protuberance is associated with
Teratoma
44
Likely diagnosis in pregnancy women with low grade fever and severe abdominal pain
Red degeneration of fibroids
45
Cancers associated with BRACA1/2
Breast and ovarian
46
Main risks for COOP
VTE, CV conditions, breast and cervical cancer
47
Ovarian cancer - 2 main risk factors
``` Many ovulations (nuliparity, early menache, late menopause) FH - BRACA 1/2 ```
48
FSH and LH in menopause
High Low oestrogen which would normally provide negative feedback as less ovarian follicles developing -> less granulosa cells
49
Endomertial cancer risk factors
``` Many ovulations (nuliparity, early menache, late menopause) High oestrogen (obesity, HRT, PCOS) DM, tamoxifen ```
50
Endometrial cancer classic symptom
Post menopausal bleeding
51
Percentage weight loss after birth that is pathogenic and management
10% Referral to midwife led breastfeeding clinic
52
Continuous dribbling incontinence after childbirth
Vesicovaginal fistula
53
Medical advantage of transdermal HRT
Reduces VTE risk
54
Cancers associated with HRT
Breast (risk normal 5 years after stopping) | Endometrial (reduced by progesterone)
55
Cabergoline
Stops lactation
56
Drug of choice to stop lactation
Cabergoline
57
Why do males not develop a uterus or other female sex organs
Anti-Mullerian hormone
58
Vaginal agenesis cause
Failure of the Mullerian ducts to properly develop
59
clomifine use
Infertility in women who do not ovulate
60
COOP increases risk of which cancers
Breast and cervix
61
HRT: adding a progesterone increases the risk of ?? and ?? UNLESS ??
Breast Ca VTE unless transdermal
62
Medical management of miscarriage
Vaginal misoprostol alone
63
Ulipristal contraindication
Severe asthma
64
Polycythemia is associated with which GOSH condition
Uterine fibroids secondary to autonomous EPO production
65
How long until IUS is effective
7 days (same as implant, IUD and Depo)
66
All women in pre-term labour should be offered ABX?
True - benzyl penicillin
67
What week before should consider IV steroids
24-34 - offer | 34-36 - consider
68
Key monitoring of women on MgSO4
Deep reflexes every 4 hours
69
When should mgso4 be given for neuroprotection
24-30 - offer | 30-34 - consider
70
Size of fibroids after menopause
Decrease (more LH and FSH)
71
Everyone should get 2 USS - at around what weeks
12 and 20

Leeds MBCHB Year 4 GOSH (10 decks)

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