General phys Flashcards
(29 cards)
Peptide hormones and growth factors act on target cells by binding to ____ receptors
Cell surface
Cholera toxins inhibits the ability of the alpha subunit of G’s to split GTP. The resulting effect is the ___ of Adenyl cycled
Stimulation
Most growth factors are :
Protein-tyrosine kinase
The first step in growth factor pathway activation is :
Receptor dimerization
Cyclic AMP is synthesized from ATP by the reaction of
Adenyl cyclase
The ip3 produced by phospholipase C acts to ?
Open calcium channels in the ER
DaG or Diacylglycerol and calcium activate
Protein kinase c
Protein kinase b regulates glycogen metabolism by ____ of glycogen synthase and thereby relieves its inhibition on glycogen synthase
Phosphorylation
If the number of ipsp’s is more than the number of esps’s on a neuron then:
Chances for an action potential triggered by the neuron decrease
Osmotic pressure of a solution decreases as the ___ content increases
H20
The phospholipid bilayer, a major component of plasma membranes is most permeable to which ion
Calcium
A protein that does not span through the entire phospholipid bilayer is
Peripheral membrane protein
The transport of water across cells in the mammalian body is primarily dependent on the:
Number of osmotically active solute particles
what happens if you add hypertonic saline solution to elf
icf volume will decrease
Insulin released from the pancreatic cell is released into the circulation and signals on a target cell by binding to the receptor and the cellular response is increased glucose uptake. The receptor Is:
Cell surface, receptor tyrosine kinases
Serum proteins in capillaries contribute to High:
Oncontic pressure in the capillaries
A physiological phenomenon that describes a responsive adjustment to an environmental stress that is irreversible and is passed through genes to the next generation
Adaptation
Increasing extra cellular K will cause the resting membrane potential to:
Increase
Make inside of cells more positive
Beta adrenergic receptor of a hepatocyte regulate glycogen metabolism. This receptor is an example of:
GPCR
In gcpr , what activates protein kinase a
Cyclic amp
Steroid hormones are usually
Transcription factors
Targets of ligand receptor complexes
insulin is secreted from the pancreas and affects glucose uptake in skeletal muscle. this is an example of ___ signaling.
endocrine
sodium potassium pump is present on the ___ of intestinal cells
basolateral membrane
a mutation of the na-k pump in a pig resulted in loss of its function; this will abolish the na gradient across the cell membrane. the glucose transport process that is affected by this defect is
co transport