General Principles Flashcards

(41 cards)

1
Q

What does cardiac coughing occur?

A

At night - compression of the corina

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2
Q

When does respiratory coughing occur?

A

During exercise / excitement

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3
Q

What do you want to ask about in a cardiac specific history?

A
Coughs
Dysnpnoea
Tachypnoea
Exercise tolerance 
Syncope
Mm colour
Resting respiratory rate
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4
Q

What is the normal respiratory rate for a dog?

A

20-30

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5
Q

How should you categories dysponea?

A

Inspiratory / expiratory
Restrictive - LRT
Or obstructive - URT

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6
Q

What should you check on a cardiac exam?

A

CO
Pulse quality, mm colour, CRT, warmth of extremities

Assess for signs of heart failure 
Forward:
- reduced pulses 
- slow CRT and pale mm
- cold extremities

Left sided congestive:

  • pulmonary crackles
  • cough
  • restrictive inspiratory and expiratory breathing pattern

Right sided congestive:

  • positive hepatojugular reflex
  • ascites
  • subcut oedema and muscle wastage
  • hepatomegaly
Cardiac auscultation 
Respiratory auscultation 
Palpate the larynx and trachea 
Thoracic percussion 
Thoracic compressibility - more useful in cats
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7
Q

What are eye clinical signs of forward heart failure?

A
= signs of poor cardiac output
Lethargy and exercise intolerance 
Weak femoral pulse
Unable to detect distal pulses
Pale MM and slow CRT
Cold extremities 
Hypothermia
Cardiogenic shock
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8
Q

How should you treat forward heart failure?

A

DO NOT GIVE FLUIDS

Give positive inotropes

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9
Q

What are the signs of right sided congestive heart failure?

A
Ascites 
Distended jugular veins
Positive hepatojugular reflex 
Pleural effusion 
Subcutaneous oedema 
Muscle wasting
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10
Q

What are the signs of left sided congestive heart failure?

A

Tachypnoea
Inspiratory and expiratory restrictive breathing pattern
Cough due to left atrial enlargement
Soft respiratory crackles on auscultation

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11
Q

What is the normal heart rate in dogs?

A

70-160

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12
Q

What is the normal heart rate in cats?

A

160-240

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13
Q

How should you describe a heart murmur?

A

PMI - left or right, base or apex
Timing - systolic, diastolic, continuous
Character - plateau, descrescendo, crescendo descrescendo, brief mid systolic, blowing
Radiation
Grade - I - VI

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14
Q

How do you grade heart murmurs?

A

I - very quiet murmur
II - murmur quieter than the heart sounds
III - murmur as loud as the hear sounds
IV - murmur louder than the heart sounds
V - louder the heart sounds and you can palpate precordial thrill
VI - louder than the heart sounds, precordial thrill, can heart murmur with the stethoscope lifted off the chest wall slightly

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15
Q

What is a diastolic gallop?

A

S3 and S4 heart sounds that are not normally audible in small animals

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16
Q

How can you auscultate diastolic gallops?

A

Using the bell of the stethoscope

Applying very little pressure over the left apex

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17
Q

What are normal lung sounds called?

A

Bronchovesicular lung sounds - harsher when there is an increased respiratory rate

18
Q

Describe some adventitious lung sounds.

A

= abnormal lung sounds

Crackles - inspiratory - smaller airways opening
Wheezes - expiratory - due to narrowed airways - pulmonary fibrosis

19
Q

What does dull thoracic percussion suggest?

A

Pleural effusion

20
Q

What does resonance on thoracic percussion suggest?

21
Q

What can reduced thoracic compressibility in a cat mean?

A

Cranial mediastinal mass

22
Q

What is preload?

A

Venous return to the heart

Determines the end diastolic stretch on the atrial cardiomyocytes before contraction

23
Q

What is afterload?

A

The resistance to ventricular ejection during systole

24
Q

What are the major consequences of congestive heart failure?

A
Oedema and effusions
Peripheral vasoconstriction 
Tachycardia
Arrhythmias
Remodelling
Fibrosis of the myocardium
25
What are the pathophysiological events that occur in response to a reduced CO in heart failure?
Vasoconstriction Increased heart rate Myocardial remodelling and fibrosis via RAAs Na+ and water retention via aldosterone - oedema and effusion
26
What adrenoreceptor as are involved in the baro-reflex?
Beta 1 adrenoreceptors
27
What cardiac decompensation does increasing the heart rate via the baroreflex cause?
Increases myocardial oxygen consumption | Reduces coronary perfusion
28
What cardiac decompensation does vasconstriction via the baroreflex cause?
Increases blood pressure
29
What does sympathetic stimulation of the beta 2 adrenoreceptors in the kidney cause?
Renin secretion
30
What is the effect of angiotensin II on the body
``` Potent vasoconstrictor Myocardial hypertrophy and fibrosis Causes ADH release Increases GFR Increases sympathetic activity Stimulates aldosterone release ``` = attempts to increase preload by increasing venous return
31
What substances in the body naturally counter-act the RAAs system?
Atrial natriuretic peptide - released following atrial stretch Brain natriuretic peptide - released following ventricular stretch - antagonise the RAAs - vasodilation, cause diuresis and sodium excretion
32
What clinical pathology tests are available for heart failure?
Pro-BNP - longer half life than normal BNP - can be assayed Endothelin - possibly a future assay
33
What are the major pathological consequences of congestive heart failure?
Oedema and effusions Peripheral vasconstriction Tachycardia / arrhythmias Remodelling and fibrosis of the myocardium
34
What are the mediators of vasoconstriction?
Noradrenaline Angiotensin II Reduced bradykinin levels vasopressin Endothelin
35
What mediators stimulate cardiac remodelling?
Angiotensin II Aldosterone Endothelin Catecholamines
36
What kind of hypertrophy does volume overload cause?
Eccentric hypertrophy = chamber dilation
37
What kind of hypertrophy does pressure overload cause?
Concentric hypertrophy - wall thickened
38
What cardiac diseases cause eccentric hypertrophy?
``` Mitral valve regurgitation Ventricular septal defects Patent ductus arteriosus Tricuspid regurgitation Anaemia Exercise ```
39
What cardiac disease cause concentric hypertrophy?
``` Aortic stenosis Systemic hypertension Pulmonic stenosis Pulmonary hypertension Exercise ```
40
Define maladaptive remodelling.
Changes in relative wall thickness + altered geometry of the heart chamber
41
Why do tachycardia and arrhythmias occur during heart failure?
Elevated catecholamine levels Increased sympathetic drive Reduced vagal tone Myocardial fibrosis and ischaemia due to remodelling