General Signs of Illness Flashcards
(44 cards)
Characterized by an increase in body temperature above normal range
Pyrexia / Fever
Transfer of heat between objects NOT in direct contact
Radiation
Removal of heat from a surface area
Evaporation
Transfer of heat through air current
Convection
Direct heat transfer
Conduction
General adaptations in insulation
-Skin
-Feather
-Fur
General circulatory Adaptations
-Vasoconstriction
-Vasodilation
General adaptations by evaporative heat loss
-Panting
-Sweating
Thermoregulation Mechanism during heatloss
-Panting
-Cutaneous vasodilation
-Postural changes
-Seeking cooler environment
-sweating
Thermoregulation during heat gain
-Catecholamine thyroxine production
-increased muscle activity
Thermoregulation during heat conservation
-Cutaneous vasoconstriction
-Piloerection
postural changes
seeking warm environment
Thermoregulatory center
pre-optic region of hypothalamus
Physiological causes of increased body temperature
Severe exercise
stress
menstruation
pregnancy
Pathological causes of increased body temperature
heat stroke
fever
Produced by variety types of pathogens: viruses, yeast, gram + & - bacteria
Exogenous pyrogens
Produced by host organisms in response to injection of external pyrogen
-what are the cytokines involved
Endogenous Pyrogens
-Interleukins 1&6, tumor necrosis factor (TNF), and interferon
Non-infectious activators are caused by
Ag-Ab complexes
- Non-infectious inflammation caused by irritants
-Etiocholanolone (steroids)
Benefits of fever
Immune function
Improved antibody productions
Activates T cells
Produces cytokines
Enhances neutrophil and macrophage function
Downside of fever
Increase cardiac output
Increased O2 consumption
Increased CO2 productions
Increased Metabolic rate
Pain
Delirium
Body temperature remains elevated above normal for a longer period (weeks or days)
Sustained/Persistent
febrile episodes lasting for 1 or more days with intervening periods of normal Body temp
Intermittent/ Undulating
Daily increase in Body temp with intervening periods of normal or subnormal temp. (Bacterial infections)
Remittent
Antipyretic agents used in the management of fever
-Acetylsalicylic acid
-Acetaminophen (contraindicated-cats)
-Dipyrone
-Flunixin meglumine (not reco in cats)
An unregulated rise in BT beyond the unchanged hypothalamic thermostatic setpoint
Hyperthermia