General Surgery Flashcards

(69 cards)

1
Q

Atelectasis

A

Partial or complete collapse of the lung, common after surgery.
Most common in elderly and overweight, smokers, symptoms or respiratory disease.
- Most common 48 hours after surgery
S/sx: Ventilation/perfusion mismatch. Decreased O2 sat. Infection (pneumonia). Fever, tachypnea, tachycardia. Elevation of diaphragm, scattered rales, decreased breath sounds.

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2
Q

GI tract wake up after abdominal surgery.

A

Small bowel first to wake at around 24 hours, stomach is next at around 48 hours, last is the colon (passing gas) at around 72 hours.

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3
Q

Ileus

A

Disruption of the normal propulsive ability of the GI tract; failure of peristalsis
Eti: - Increased sympathetic activity in GI tract because post surgery there are inhibitory neural reflexes on spinal afferent signals.
- Nitric oxide, vasoactive intestinal polypeptide, and maybe substance P thought to act as inhibitory neurotransmitters in the gut.

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4
Q

Post surgical bowel obstruction

A

Eti: illeus, or internal hernia or adhesions.
S/sx: - Moderate, diffuse abdominal discomfort
- Constipation
- Abdominal distention
- N/V, especially after meals
- No BM or farting
- Lots of burping
Manage:
- Pain management, replacement fluid therapy, electrolyte replacement, nutritional support, continue abdominal examinations, gastrografin
- Bowel rest (clear fluids etc.)

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5
Q

DVT

A

Etiology: Virchow’s triad: venous stasis, hyper-coagulability, endothelial injury.
S/sx: leg pain, swelling, homens sign, etc.
Manage: LMWH

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6
Q

Pulmonary embolism

A

Eti: often from DVT
S/sx: Dyspnea unexplained by auscultatory findings, ECG changes (S1Q3T3- large S wave in lead 1, Q waves in lead 3, inverted T waves in lead 3 indicates acute right heart strain). Pain in the thorax between clavicles.
Manage: warfarin for long term anticoag, fibrinolysis may be indicated for massive PE.

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7
Q

Post surgical bowel obstruction

A

Eti: failure of post-op return of bowel function, adhesions, or internal hernia.
s/sx: abdominal pain, no flautus or bowel movements, vomiting back food.
Tx: Nasogastric suction, laparotomy

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8
Q

IV phlebitis

A

Eti: inflammation in vein after needle placement for extended period.
Timeline: most common reason for post-op fever after day 3.
S/sx: triad: induration, edema, tenderness.

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9
Q

What are the five w’s of post op fever?

A

Wind: atelectasis or pneumonia
Water: UTI
Wound: Superficial, intra-abdominal abscess, peritonitis etc.
Walking: DVT/PE
Wonder drugs: drug fever, pseudomembranous colitis

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10
Q

Atelectasis POF

A

Presentation time: first 24 hours
S/sx: Isolated fever, tachypnea, dyspnea and or tachycardia
Dx: chest x-ray
Tx: Pulmonary hygiene (suction, chest physiotherapy, nasotracheal suction), admit if patient is ill appearing

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11
Q

Pneumonia POF

A

Presentation time: 3-7 days Postop
S/sx: dyspnea, chest pain, fever, productive cough, and or tachypnea
Dx: chest x-ray
Tx: Admission and treat with broad-spectrum abx

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12
Q

Pseudomembranous colitis POF

A

Aka: C. diff, can present any time
S/sx: Fever, abdominal cramps, diarrhea, pus or mucus in stool, nausea, dehydration
Dx: stool testing using immunoassay
Tx: Vancomycin

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13
Q

3 or 4 stages of wound healing

A

3: inflammatory, fibroblastic, maturation
4: hemostasis, inflammatory, proliferation, remodling

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14
Q

Pyomyositis

A

Eti: purulent infection of skeletal muscle from hematogenous spread, usually from abscess formation
Timeline: 3 stages
S/sx: fever, pain, cramping localized to single muscle group.
Stage 1: swelling, local muscle pain
Stage 2: 10-21 days: fever, exquistie muscle tenderness, edema, frank abscess may be visible, leukocytosis
Stage 3: systemic toxicity
Eval: X-ray, lab data, T2 weighted MRI

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15
Q

necrotizing fasciitis

A

Eti: Type 1: polymicrobial, type2: group A strep.
- Infection of deeper tissues, desctruction of muscle facia over subQ fat.
S/sx: skin color change from red-purple to patches of blue-gray

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16
Q

gas gangrene

A

Eti: Most often: Clostridium perfringes
S/sx: severe pain, numbness, confusion, flu-like symptoms, skin color change, crepitus of skin
Eval: image that shows gas w/i soft tissue
Tx: surgical debridement and soft tissue reconstruction

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17
Q

cellulitis

A

Eti: Mostly GABHS and staph, involves the deeper dermis and subQ fat
S/sx: warm, edema, erythema
Eval: blood culture if concerned about systemic toxicity
Management: Abx PO, Abx IV if systemic

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18
Q

Stages of skin ulcers

A

Stages:

1: Skin intact but with non-blanchable redness for greater than 1 hour after relief of pressure
2: Blister or other break in the dermis with partial thickness loss
3: Full thickness tissue loss. SubQ fat may be visible; destruction extends into the muscle
4: Full thickness tissue loss with involvement of bone, tendon, or joint. Includes undermining and tunneling.

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19
Q

Achalasia

A

Eti: Loss of peristalsis in distal 2/3rds of esophagus and impaired LES relaxation. Loss of myenteric plexus neurons.
S/sx: dysphagia for both liquids and solids, (gradual and progressive)
- regurgitation of undigested food
- heartburn, not due to GER, but stasis of undigested food in esophagus
- chest pain, usually with a meal
Dx: EGD, barium swallow (birds beak), esophageal manometry (gold standard)
Tx: Pneumatic dilation, surgical (heller myotomy and partial fundoplication)

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20
Q

Esophageal varices

A

Eti: portal hypertension caused by cirrhosis, up to 80% of patients with portal hypertension will eventually develop.
S/sx: Asymptomatic until rupture. Upper GI bleed: hematemesis, melena, may have hypovolemia. Cirrhosis on exam.
Dx: EGD shows enlarged veins.
Tx: initial: IV fluids, transfusion, if coagulopathy: FFP, vit K, empiric abx (usually 3rd gen cephalosporin).
- Vasoconstrictive drugs (octreotide),
- Endoscopic variceal ablation
- Ballon tamponade (when other techniques don’t work)

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21
Q

Zenker’s diverticulum

A

Eti: Progressive herniation of the mucosa and submucosa through the Killian triangle.
Presentation: dysphagia, regurgitation of undigested food, halitosis, GERD, gurgling sounds in neck, may present with aspiration pneumonia
Dx: Barium swallow
Tx: not required if asymptomatic, surgery: CP myotomy w/ diverticulectomy

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22
Q

Esophageal carcinoma

A

Eti:adenocarcinoma: GERD: most common predisposing factor
- Squamous cell carcinoma: smoking, ETOH, chronic indigestion
Sx: Dysphagia, initially solids, later liquids, weight loss, odynophagia, hoarseness, respiratory symp
Dx: Barium swallow (usually presents as intraluminal mass or stricture, EGD for biopsy

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23
Q

Barrett’s esophagus

A

Eti: GERD + shorter/weaker LES, associated with hiatal hernias
Risks: Long history of GERD, h pylori gastritis, smoking, obesity
Dx: EGD, barium swallow etc.
Tx: PPIs or fundoplication (preferred), but still need surveillance, q12-24 months

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24
Q

Caustic injuries to esophagus

A

Eti: ingestion of caustic solution, usually suicide attempt, or accident in kids
Sx: inflammatory edema of lips, mouth or tongue, chest pain, dysphagia, drooling, hematemesis, dysphagia etc.
Dx: CXR, esophagogram
Tx; Depends on severity

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25
Hiatal hernia
Eti: obesity, aging, generally weakening of musculofascial structures. Sx: dysphagia, epigastric discomfort, anemia, heartburn, regurg, post-prandial bloating, resp sympt Dx: Barium swallow, EGD Tx: surgery if symptomatic (nissen fundoplication)
26
Perforation of esophagus
Eti: Iatrogenic, severe vomiting, external trauma Sx: cervical: neck pain, crepitus, dysphagia, signs of infection - thoracic: tachycardia, tachypnea, dyspnea, hypotension... Dx: Xray, esophagogram, CT chest, thoracentesis Tx: Broad spectrum abx, surgery within 24 hours,
27
Schatzes ring
Eti: associated with GERD and hiatal hernias Sx: dysphagia to solid food, especially large boluses - intermittent, not progressive Dx: barium esophogram is more sensitive than EGD Tx: endoscopic dilation, or endoscopic electrosurgical incision
28
Bacterial peritonitis (primary)
Eti: hematogenous or lymphogenous spread, or from the gut or fallopian tubes... Presentation: abrupt onset of fever, abdominal pain, distention, rebound tenderness Dx: fluid from paracentesis: used for gram stain, culture, serum ascities albumin gradient, ect. Tx: empiric, third gen ceph
29
Bacterial peritonitis (secondary)
Eti: GI perforation, ischemic bowel, IBD, appendicitis, trauma, PID, peritoneal dialysis Sx: abdominal pain and rigidity, N/V, anorexia, fever, rebound tenderness. Changes in bowel function, character of pain, location, etc. depend on cause Dx: paracentesis eval... Tx: abx with anaerobic coverage
30
Intra-abdominal abcess
Eti: GI perforations, postop complications, penetrating injuries, sequela of peritonitis Sx: fever, tachycardia, pain, prolonged ileus after surgery or peritonitis Dx: CT is best Tx: abx and drainage Surgical: operative drainage if no improvement after percutaneous
31
Retroperitoneal abcess
Eti: injury or infection of adjacent structures Pres: fever, abdominal pain, flank pain, anorexia, N/V, weight loss. May have thigh and back pain. + iliopsoas sign if located near psoas muscle Dx: CT is best Tx: abx and drainage
32
Ascities
Eti: disease of the peritoneum, or CHF, cirrhosis, Budd-chiari, et. Pres: fluid wave, scrotal edema, umbilica or inguinal hernia, plural effusion, peri-umbilical nodule (sister mary joseph, or supraclavicular nodule (malignancy). Dx: US or CT, paracentesis
33
Peptic ulcer disease
Eti: decrease of the mucosa in gastric ulcers, increase in acid or pepsin in duodenal ulcers. Major causes: H. pylori, NSAIDs, Sx: gnawing dull ache, hunger like pain DU: better after meal, worse on empty stomach GU: worse after meal Complications: “coffee ground” emesis, hematemesis, melena Dx: EGD
34
Zollinger-Ellison syndrome
Eti: gastrin-secreting gut neuroendocrine tumors (gastrinomas), which result in hypergastrinemia and acid hypersecretion Sx: multiple ulcers, "kissing ulcers" Dx: fasting serum gastrin, Secretin stimulation test
35
Mallory-Weiss tear
Eti: cough, vomiting, heavy lifting, seizures sx: history of non-blooding vomiting followed by hematemesis, melena, epigastric pain radiating to the back Dx: EGD Tx: Endoscopic therapy
36
Gastric carcinoma
Eti: H pylori; also salted, cured, smoked, or pickled foods containing nitrites Sx: Indigestion, weight loss, early satiety, abdominal pain/fullness, nausea, post-prandial vomiting, dysphagia, melena, hematemesis, anemia Dx: EGD, CEA (carcinoembryoic antigen) elevated TX: preop chemo, surgery
37
pyloric stenosis
Eti: hypertrophy & hyperplasia of the muscular layers of the pylorus, causing a functional outlet obstruction Epi: most often first 3-12 weeks of life Sx: non-bilious, projectile vomiting Dx: abdominal US,
38
Hepatic trauma
Eti: Blunt or penetrating trauma S/sx: Hypovolemic shock, hypotension, decreased uriniary output, low central venus pressure, sometimes abdominal pressure Dx: FAST exam, high res CT with contrast, may have leukocytosis, coagulopathy, acidosis... Tx: Ensure hemodynamic stability, often requires surgical management.
39
Liver cancer
Eti: hepatocellular carcinoma, cancer arising from hepatocytes, or intrahepatic cholangiocarcinoma, cancer arising from biliary epithelial cells. Risk: Hep B and C Eval: AST and ALT may be elevated, but are non-specific, may have elevated alk phos. Image.
40
Cholecystitis
Eti: 80% of acute from obstruction of the cystic duct by a gallstone. S/sx: Acute RUQ pain, fever and Eval: US with sonographyic murphy sign, PMNs and leukocytosis. Tx: most cases resolve spontaneously
41
Cholagnitis
Eti: Bacterial infection of biliary ducts, always as sign of biliary obstruction, often caused by choledocholithiasis, biliary stricture and neoplasm. S/sx: Charcot's triad: biliary colic, jaundice, chills and fever Eval: US, may also need ERCP Manage: IV abx, often: cefazolin, cefoxitin, surgical if severe or unremitting.
42
Choledocolithiasis
Eti: gallstone in common bile duct S/sx: Biliary type pain. Dx: Labs (AST/ALT, serum bilirubin, alk phos, GGT), transabdominal US, MRCP, ERCP Tx: Removal of stone
43
Pancreatitis
Eti: non-bacterial inflammatory disease, caused by activation, interstitial liveration, autodigestion of pancrease by its own enzymes. Most is caused by gallstones and ETOHism. S/sx: acute sudden, super abdominal pain, nausea, vomiting and elevated serum amylase. Dx: Can have elevated Hct with edematous pancreas, serum amylase 3x normal. (lipase is specfic to pancreas). Tx: Reduce pancreatic secretory stimuli, correct electrolyte balance. Surgical: Endoscopic sphincterotomy, surgery C/I in acute pancreatitis
44
pancreatic pseudocyst
Defined fibrous wall but lacks epithelial lining. Eti: encapsulated collection of fluid with high enzyme concentrations arising from pancreas. S/sx: Epigastric mass and pain, mild fever, persistant serum amylase. Should be considered when acute pancreatits last more than a week. Tx: Expectant management is reasonable, spontaneous resolution in about 40% of cases.
45
Pancreatic abscess
Fatal if not treated surgically. Eti: Develops in severe cases of pancreatitis w/ hypovolemic shock and pancreatic necrosis. Often seen in post-op pancreatitis. S/sx: rising fever, lack of improvement of severe acute pancreatitis. Can have some vomiting or jaundice. Often just fever. Eval: Serum amylase may be elevated, leukocytosis. Tx: Infected fluid must be drained by percutaneous catheter drainage. Post-op abx to cover for E. coli, staph, klebsiella, proteus, candida albicans.
46
What is Ranson's criteria?
``` Estimates mortality of patients with pancreatitis based on 48 hour lab values. (0-11 points, 7 points = 100% mortality. On admin: - WBC greater than 16k - Age greater than 55 - Glucose greater than 200 - LDH greater than 250 48 hours into admin: - HCT drop >20% - BUN increase >5mg/dL - Ca<8mg/dL - Arterial pO2 <60mmgH ```
47
Acute appendicitis
Eti: Obstruction of the appendix by a fecalith, inflammation, foreign body, or neoplasm S/sx: vague/colicky periumbilical pain, N/V, anorexia, fever, constipation Dx: leukocytosis w/ neutrophilia, microscopic hematuria and pyruria, CT abdomen/pelvis Tx: peroperative broad-spectrum abx w/ gram neg and anaerobic coverage
48
blind loop syndrome
aka: small intestine bacterial overgrowth Eti: failure to limit bacterial growth. Structural lesions causing stasis, IBD, scleroderma S/sx: diarrhea, steatorrhea, distention, abd discomfort, weight loss, dyspepsia Dx: culture and breath test Tx; augmentin or flagyl
49
Short bowel syndrome
Most common after after large resection due to AMI. Usually occurs in patients with less than 100cm of bowel remaining. S/sx: diarrhea, steatorrhea, dehydration, weakness, fatigue.
50
Small bowel obstruction
Eti: Most often due to adhesions related to prior abd. surgery. Hernia, neoplasm, IBD. ABCs: adhesions, bulge (hernia), cancer S/sx: N/V, colicky abd. pain, obstipation, abdominal distension ...
51
Large bowel obstruction
Eti: Colon cancer, diverticulitis, volvulus Pathophys: Obstruction = mucosal edema = impaired venous and arterial blood flow to bowel. S/sx: Obstipation, vomiting, deep visceral cramping Dx: abdominal XR, CT w/ rectal contrast, contrast enema Tx: Hydration, TPN Surgery: Removal of necrotic bowel, or obstructing lesion
52
Acute mesenteric vascular occlusion
Eti: Sudden decrease of mesenteric blood supply, inadequate perfusion, most commonly by embolus Epi: CVD greatest risk S/sx: Severe abdominal pain out of proportion of physical findings, poorly localized. N/V/D Dx: Urgent CTA, mesenteric arteriography Labs: WBC, metabolic acidosis, elevated lactate
53
Colon cancer
Eti: adenomatous polyp into malignancy, 3rd leading cause of cancer death. Epi: Lynch syndrome S/sx: Fe def anemia, rectal bleeding, abdominal pain, change in bowel habits, obstruction, majority asymp. Dx: colonoscopy, barium enema, CT cap, elevated CEA
54
diverticulosis
Eti: weakness in bowel wall Epi: 50-60% of adults by 60. M=W S/sx: uninflammed diverticula, usually asymp, LLQ tender, palpable left colon, sigmoid most common site.
55
Diverticultitis
Eti: micro or macroscopic perforation/ obstruction of a diverticulum = inflam response Epi: avg age: 62 S/sx: fever, LLQ pain, N/V, constipation or diarrhea, flatulence, bloating Dx: CT abd pelv., elevated WBC, colonoscopy Tx: clear liquid diet, broad spectrum abx (cipro + flagyl or augmentin
56
Volvulus
Eti: rotation of segment of the LI S/sx: colicky pain V, obstipation Dx: XR: coffee bean sign, birds beak sign Tx: fluid, electrolytes, surgical emergency
57
Perirectal abscess
Eti: infection in cryptoglandular epithelium lining the anal canal S/sx: perirectal pain worse with movement or sitting
58
Anorectal fistula
Eti: can develop from perirectal abscess | ...
59
Pilonidal cyst and abscess
Eti: hair containing cyst located just below the coccyx S/sx: painful swollen lesion in sacrococcygeal region Tx: I&D, if abscess = abx
60
Crohn's vs Ulcerative colitis S/sx?
UC: Limited to the colon, rectum always involved. C: any where from mouth to anus, TERMINAL ILEUM mc. Urgency, tenesmus, incontinence, 4 stools per day to 10 severe. C: healthy areas between inflamed areas. UC: Continuous inflam of colon. UC: only effects innermost lining of bowel C: Can have symptoms for many years before dx. UC: Usually gradual onset of symptoms over a couple of weeks. UC: Bloody stool in more common, bloody diarrhea
61
Extraintestinal symptoms of ulcerative colitis
MSK:arthritis, large joints, ankylosing spondylitis, osteoporosis, Eye: uveitits and episcleritis Skin: erythema nodosum, pyoderma gangrenosum Hepatobiliary: primary sclerosingcolagnitis, fatty liver,autoimmune liver disease Hematopoietic/coag: venous and arterial thromboembolism Pulmonary: rare
62
Extraintestinal symptoms of crohns
fatigue, weight loss, MSK: arthritis, Eye: uvetitis Skin: erythema nodosum, pyoderma gangrenosum Hepatobiliary: primary sclerosising cholagitits renal stones, VTE, ATE
63
Work up for UC
CBC for anemia Elevated ESR Low albumin Electrolyte abnormalities (due to dehyrdation from diarrhea) Abdominal radiography: "thumbprinting" secondary to edema and colonic dilation Avoid barium enema for risk of ileus with toxic megacolon
64
UC v C: different signs on colonoscopy etc.
Colonoscopy: UC: ulceration in rectum, sandpaper appearance. C: Skip lesions, cobblestone appearance. Barium studies: UC: Stove pipe sign (loss of haustral markings) C: String sign: narrowed due to transmural stricutres
65
UC v C: Complications
UC: - primary sclerosing cholangitis, colon CA, toxic megacolon. (smoking decreases risk for UC) C: Perianal dz: fistulas, stricture, aabscess, granulomas
66
What does ERCP stand for
Endoscopic Retrograde Cholangiopancreatography
67
Types of polyps
Pseudopolyps: due to IBD (non-cancerous) Hyperplastic: low risk, 90% of all polpys Adenomatous polyps: 10% of polyps, 10-20 years before becoming cancerous - Tubulous adenoma: nonpedunculated - Tubulovillous (mixture) - Villous adenoma: (highest risk) tend to be sessile
68
Umbilical hernia
Risk: more common in women, multiple pregnancy, ascites, obesity Findings: bulge at umbilicus, can have patient sit up, or valsalva to elicit popping out.
69
Staging of breast cancer
``` TNM: T: Primary tumor: size and if in situ or moved N: lymph nodes: regional involvement M: metastatsis Stage 0: T in situ, N0, M0 Stage 1: T1 (<5 cm big), N0, M0 Stage IIA: T0-T2, N1, M0 Stage IV: includes M1 ```