generated by AI -Canine pancreatitis Flashcards

1
Q

What is elastography?

A

○ Noninvasive imaging technique
○ Assesses tissue mechanical properties like stiffness
○ Uses sound waves
○ Detects differences in stiffness between healthy and diseased tissues

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2
Q

How was elastography investigated in dogs with suspected acute
pancreatitis?

A

Shear wave velocity was higher in dogs with suspected AP compared to controls

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3
Q

What is computed tomography angiography (CTA)?

A

○ Utilizes iodinated contrast material
○ Evaluates blood flow in organs and tissues
○ Rapid image acquisition with multislice CT

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4
Q

What are the imaging findings in acute pancreatitis on CTA?

A

○ Enlarged pancreas
○ Hypoattenuating appearance
○ Heterogeneous contrast enhancement indicating decreased vascularity

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5
Q

How does CTA compare to abdominal ultrasound in identifying severe acute
pancreatitis and portal vein thrombosis?

A

○ CTA is superior in identifying severe AP and portal vein thrombosis

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6
Q

What is the sensitivity and specificity of the Spec cPL assay in dogs with
gastrointestinal disease?

A

○ Sensitivity: 85.7% to 90.9%
○ Specificity: 64.0% to 74.3%

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7
Q

What are some routine clinicopathological features of acute pancreatitis in
dogs?

A

○ Dehydration reflected by increased PCV and total protein
○ Elevetedtotal protein or Hypoproteinemia due to acute phase response or protein loss
○ Thrombocytopenia from inflammation
○ Left shift in neutrophils
○ Increased acute phase reactants and inflammatory cytokines

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8
Q

How can serum biochemistry profile help in diagnosing acute pancreatitis in
dogs?

A

○ Azotemia may indicate AKI
○ Increased liver enzyme activities due to hepatic changes
○ Hypocalcemia may occur secondary to other factors

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9
Q

What is the role of symmetric dimethylarginine (SDMA) in detecting acute
kidney injury secondary to acute pancreatitis?

A

SDMA may be a more sensitive biomarker for AKI secondary to Ap

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10
Q

How can a blood smear evaluation be important in diagnosing acute
pancreatitis in dogs?

A

Left shift in neutrophils may be present even without increased WBC count

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11
Q

What are some clinical and prognostic findings in dogs with suspected
extrahepatic biliary obstruction and pancreatitis?

A
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12
Q

What is the role of C-reactive protein in canine acute pancreatitis?

A

C-reactive protein concentrations may be increased in canine acute pancreatitis,can be used to minitore response to tx

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13
Q

What is the clinical scoring system developed for short-term
prediction of death in dogs with acute pancreatitis?

A
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14
Q
A
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15
Q

What are some key recommendations for the diagnosis and management of
canine pancreatitis?

A

Update on the diagnosis and management of canine pancreatitis

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16
Q

What are some potential applications of experimental models and human
medicine in understanding the pathophysiology of acute pancreatitis in dogs?

A

Potential applications from experimental models and human medicine to dogs in
understanding the pathophysiology of acute pancreatitis

17
Q

What is the role of elastography in diagnosing acute pancreatitis in dogs?

A

Elastography is a noninvasive imaging technique that can detect differences in tissue
stiffness between healthy and diseased tissues

18
Q

How does computed tomography angiography (CTA) help in evaluating acute
pancreatitis in dogs?

A

CTA utilizes iodinated contrast material to better evaluate blood flow in organs and
surrounding tissues, providing detailed imaging of the pancreas in cases of acute
pancreatitis

19
Q

What are some of the routine clinicopathological features that can aid in the
diagnosis of acute pancreatitis in dogs?

A

● CBC findings reflecting dehydration and inflammation
● Serum biochemistry profile showing hepatic changes and potential kidney injury
● Evaluation of acute phase reactants and inflammatory cytokines

20
Q

How can the integration of clinical signs, laboratory findings, and imaging
techniques aid in the effective diagnosis of acute pancreatitis in dogs?

A

Integration of clinical signs, laboratory data, and imaging findings is essential for an
accurate diagnosis of acute pancreatitis due to the nonspecific nature of clinical signs