Generic/Brand Flashcards
(71 cards)
1
Q
Amaryl
A
Glimepiride
2
Q
Glucotrol
A
Glipizide
3
Q
DiaBeta
A
Glyburide micronase
4
Q
Glynase
A
Glyburide micronized
5
Q
Avandia
- FDA removed restriction on
- BBW
A
Rosiglitazone
- FDA recently removed restriction below
- Avandia-Rosiglitazone Medicines Access Program: will only be available thr a special mail-order. MDs and pts are enrolled. Special pharmacies are part of the program, and will be the only pharmacies that can mail the drugs
- BBW: possible HF
- can lead to ischemic HF
6
Q
Actos
A
Pioglitazone
7
Q
Precose
- Administration
A
Acarbose
- Give with 1st bite of meal
8
Q
Starlix
- Direction for administration
A
Nateglinide
- Give 30 min b/4 meals
- Skip meal/skip dose & add meal/add dose
9
Q
Cycloset
- Indication
A
Bromocriptine
- Indication: DM
10
Q
Afrezza
- CI:
- SEs
- Storage
- Exp at RT:
- Exp of opened strips:
- Cartridge:
A
RA insulin human inhalation powder
- CI: any lung disease => lung cancer, asthma
- SEs: HypoG, cough/bronchospasm, hypoK, fluid retention/HF
- Storage: fridge
- Exp at RT: 10 days
- Exp of opened strips: 3 days
- Cartridge: leave at RT x 10min before use
11
Q
Humalog
- Class
A
Lispro
- RA insulin
12
Q
Novolog
- Class
A
Aspart
- RA insulin
13
Q
Apidra
- Class
A
Glulisine
- RA insulin can give IV in hospital w/ monitoring
14
Q
Short Acting Insulin:
- Drugs in this class
- Appearance:
- Expiration at RT
A
Regular insulin (OTC)
- Humulin R => RT 31 days
- Novolin R => RT 42 days
- Appearance: clear
15
Q
Intermediate Acting Insulin:
- Drugs in this class
- Appearance:
- Expiration at RT
A
NPH (cloudy) (OTC)
- Humulin N => RT Exp 31 days
- Novolin N => RT Exp 42 days
16
Q
Detemir
- Frequency
- Exp date at RT:
A
Levemir
- Give BID
- Exp in 42 days
17
Q
Lantus
- Frequency
- Mixing direction
- Exp date at RT:
A
Glargine
- Give QD
- NEVER mix w/ other insulins => pH is 4
- Exp: 28 days
18
Q
Symlin
- Indication
- Do not give
- Dose
Type I and Type II - MOA
- SEs
- Storage
- Exp:
A
Pramlintide - Pen
- Indication: postprandial glycemic control
- Do not give to: hypersensitivity to metacresol preservative, gastroparesis or on GI motility med, on alpha glycosides inhibitors
- Dose
Type I: 15 mcg
Type II: 60 mcg - MOA: increase AMYLIN = delay gastric emptying, inhibits postprandial glucose release, reduce appetite
- SEs: HypoG, anorexia, wt loss, nausea
- Storage: fridge
- Exp: 30 days at RT
19
Q
Diabinese
- Class
A
Chlorpropamide
- Class: 1st generation of Sulfonylureas
20
Q
Tolinase
- Class
A
Tolazemide
- Class: 1st generation of Sulfonylureas
21
Q
Orinase
- Class
A
Tolbutamide
- Class: 1st generation of Sulfonylureas
22
Q
Glucophage
Glucophage XR
A
Metformin
- Max dose:
Glucophage 2550mg/d
Glucophage XR: 2000mg/d
23
Q
Glucovance (R)
A
Glyburide/Metformin
24
Q
Avandamet (R)
A
Rosiglitazone/Metformin
- Avandia = Rosiglitazone
25
Trajenta
====
Jentadueto
Linagliptin
===
Linagliptin/Metformin
26
Actoplus Met
Pioglitazone/Metformin
Actos = pioglitazone
27
Prandin
===
Prandimet
Repaglinide
====
Repaglinide/Metformin
28
Onglyza
====
Kombiglyze XR
- Max dose
Saxagliptin
===
Saxagliptin/metformin ER
-Max dose: Max 5mg sax & 2000 mg ER metformin
29
```
Avandia
===
Amaryl
===
Avandaryl
```
```
Rosiglitazone
===
Glimepiride
====
Rosiglitazone and Glimepiride
```
30
Prandin
- Administration direction
Repaglinide
- Give 15 min b/4 meal
- Skip meal/skip dose & add meal/add dose
31
Glyset
- Administration direction
Miglitol
- Give with 1st bite of meal
32
Januvia
- Frequency
- Caution SE:
- Use with Digoxin:
Sitagliptin Phosphate
- QD
- Can cause acute pancreatitis
- Use w/ digoxin: increase digoxin level
33
Onglyza
- Dose and frequency
- Strong inhibitor or Inducer?
Saxagliptin
- Dose: 2.5-5mg QD
- Strong inhibitor of 3A4/5
34
Tradjenta
- Dose
Linagliptin
- 5mg QD
- 3A4 substrate
35
Janumet
- Administration
Sitagliptin + Metformin
- Adm: with meal(s)
36
Jentadueto
- Administration
Linagliptin + Metformin
- Adm: BID w/ meals
37
Juvisync
Sitagliptin + Simvastatin
38
Nesina
- Caution SEs:
- DDI
**Alogliptin
- Pancreatitis, hypoG
- NO DDI.
39
Kazano
Alogliptin + Metformin HCl
40
Oseni
Alogliptin + Pioglitazone
41
Byetta
- Warning
Exenatide Injection
- Warning: acute renal failure/pancreatitis
- Report any abd pain
42
Bydureon
- Frequency
Exenatide ER
| - 2mg powder injection weekly
43
Victoza
- Storage
* Open
* Unopened
- Color:
Liraglutide Pen
- Storage: Refrigerator for unopen.
Open @ RT for 30 days. Protect from light
- Color: clear. do not use if not clear
44
Drugs belong to incretin enhancers
Byetta
Januvia
Onglyza
Victoza
45
Incretin Enhancers
Drugs help pt lose weight (incretin class)
Byetta
| Victoza
46
Incretin Enhancers
Drugs that are neutral in weight
Januvia
| Onglyza
47
Cause Pancreatitis
LEAS
- Sitagliptin
- Alogliptin
- Exenatide
- Linagliptin
48
Preg Cat B
- Linagliptin (tradjenta)
- Glyburide
- Metformin
49
Drugs in Na-G co-transporter 2 (SGLT2) inhibitor class:
- Canagliflozin (Invokana)
| - Dapagliflozin (Farxiga)
50
Invokana
===
Invokamet
Canagliflozin
====
Canagliflozin/Metformin
51
Farxiga
Dapagliflozin
52
Invokana
- Indication
- MOA:
- Dosage form:
- Administration
GFR > 60:
GFR 45-59:
GFR
Canagliflozin
- Indication: Type II
- MOA: SGLT2 inhibitor => increase urinary glucose excretion
- Form: Film coated tabs
- Dose: initial 100 mg PO QD before 1st meal
GFR > 60: can incr dose to 300 mg QD
GFR 45-59: Max 100mg QD
GFR
53
Canagliflozin
- Caution
- Symptomatic hypoTN
- Increase SCr
- Increase K
- Increase LDL
- HypoG
- Genital fungal infection
54
Farxiga
- Indication
- MOA:
- Dosage form:
- Administration
GFR
Dapagliflozin
- Indication: type II DM
- MOA: SGLT2: increase urinary glucose excretion
- Form: tablet
- Dose: 5mg QD, QAM with or w/o food. Dose can be increase to 10mg QD if needed
- GFR
55
Santyl Ointment
- Indication
Collagenase
- FDA approves active enzymatic therapy that continuously removes necrotic tissue from wounds at the microscopic level, which allows new, healthy tissue to form.
56
SGLT2 => renal imp
- Which one should not use
- Which one need dose adj
- Not use: Farxiga (Dapagliflozin)
| - Need dose adj: Invokana. Avoid when CrCl
57
Insulin dose
- Type I
- Type II
- Type I: 0.5-0.8u/kg
| - Type II: 0.7-1.5u/kg
58
Manage hypoG in unconscious pt
- Glucagon: 1mg SC/IM/IV
| - Glucose IV 10-25g 4 min followed by 5-10 g/hr until pt gain consciousness
59
Trulicity
- Class
- Frequency
Dulaglutide
- Class: GLP-1 Inhibitor
- Frequency: weekly
60
Jardiance
- Class
Empagliflozin
- Class: SGLLT-2 inhibitor
61
Riomet
Metformin oral sol'n 100mg/mL
62
Fortamet
- Form
- Max dose
Metformin ER
- Max dose: 2500mg/day
63
Glumetza
- Max dose:
Meformin
- Max Dose: 2g/d
64
Prandimet
- Administration
Repeglinide + Metformin
- Take 30 min before mal
- Skip meal, skip dose
65
Kombiglyze XR
- Frequency
Saxagliptin + metformin
- QD in the evening
66
Kazano
Alogliptin + Metformin
67
Invokamet
Canagliflozin + metformine
68
Xigduo XR
Dapagliflozin + metformin
69
Avandaryl
Rosiglitazone + Glimepiride
70
Tanzeum
- Class
- Frequency
Albiglutide
- Class: GLP-1 inhibitor
- Dose: weekly
71
Parlodel
- Indication
Bromocriptine
- Indication: Parkinson disease
