Genes, Proteins, and Cell Division Flashcards

(33 cards)

1
Q

Making a mRNA copy of a gene is known as what?

A

Transcription.

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2
Q

What a the 3 main parts of a gene?

A

The promotor, the coding sequence, and the the terminator.

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3
Q

The process of producing a protein from mRNA is known as what?

A

Translation.

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4
Q

Which strand of DNA is used to make mRNA?

A

The template strand.

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5
Q

Before mRNA can be translated into proteins, what must happen?

A

It must be processed, i.e.Introns must be removed by splicing.

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6
Q

What is a codon?

A

A sequence of 3 base pairs that codes for an amino acid.

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7
Q

What is meant by the genetic code?

A

The 4 letter code of DNA can represent 20 different amino acids by different combinations in a codon, i.e. there are 64 possible combinations.

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8
Q

Codons in mRNA are recognised by anticodons on what molecule?

A

tRNA.

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9
Q

What are the 3 steps in translation?

A

Initiation, elongation, termination.

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10
Q

What are the phases of the cell cycle?

A

Growth 1 (G1), Syntheses (S), Growth 2 (G2), Mitosis (M).

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11
Q

During which phase is DNA replicated?

A

The S phase.

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12
Q

During which phase are organelles duplicated?

A

G1 phase.

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13
Q

What is meant by semi-conservative replication?

A

Each new double stranded DNA contains half of the old strand of DNA.

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14
Q

What are the stages of mitosis?

A

Prophase, metaphase. anaphase. and telephase.

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15
Q

The nuclear envelope disappears in what stage?

A

Prophase.

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16
Q

During anaphase the 2 sister chromatids are pulled apart by attaching to what?

A

Microtubules of the mitotic spindle.

17
Q

What are the 3 fates of a cell?

A
  1. To remain alive and functioning without dividing.
  2. To grow and divide.
  3. To die.
18
Q

What is the importance of checkpoints in the cell cycle.

A

To halt division if conditions are not right, e.g. if the DNA hasn’t been copied properly or there are not enough nutrients.

19
Q

What is the difference between apoptosis and necrosis?

A

Apoptosis is programmed cell death and doesn’t disrupt surrounding cells, necrosis is uncontrolled cell death that harms surrounding cells due to spillage of cell contents.

20
Q

How many chromosome pairs do humans have?

21
Q

A variant of a gene is known as what?

22
Q

When an individual has 2 identical alleles of the same gene they are said to be what?

23
Q

What does it mean when a cell is duploid or haploid?

A

Duploid means 2 copies of each chromosome, haploid means only one copy.

24
Q

What is a trait?

A

An observable feature of an organism, e.g. eye colour.

25
What is meant be a dominant trait?
Only one copy of the gene is needed for the trait to appear.
26
What is the difference between phenotype and genotype.
A phenotype is the observable end-product of genes, i.e. a trait, while a genotype is the genetic sequence itself.
27
If parents are heterozygous for a certain gene, i.e. they both have a dominant B gene and a recessive b gene, what is the probability of a child being homozygous for the recessive trait?
25%
28
What is meant by a homologous gene or chromosome?
They code for the same proteins, even though there may be variance in the exact sequence.
29
What is the law of segregation?
Genes pairs are transferred to gametes with equal probability.
30
What is the law of independent assortment?
Each gene is transferred to a gamete independently of others, i.e. the probability of gene A being transferred to the gamete does not affect the probability of the B gene being transferred, as long as they're on different chromosomes.
31
What can we use to trace a trait from a family history?
A pedigree chart.
32
What kind of inheritance pattern does this pedigree chart show?
Autosomal dominant. The trait is found in every generation and affects both sexes equally.
33
What inheritance pattern does this chart show?
Autosomal recessive. Two unaffected parents gave an affected child and it affects both sexes equally.