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Pato Genes > Genes Supresores > Flashcards

Genes Supresores Flashcards

1
Q

Inhibidores de las señales mitogénicas

A

➔ APC
➔ NF1
➔ NF2
➔ PTEN
➔ SMAD2, SMAD4

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2
Q

Inhibidores de la progresión celular

A

➔ RB

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3
Q

Inhibidores del pro-crecimiento y angiogenia

A

VHL

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4
Q

Inhibidores de la invasión y metástasis

A

CDH1 (Cadherina E)

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5
Q

Genes facilitadores de la estabilidad genómica

A

p53

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6
Q

Genes supresores de mecanismo desconocido

A

➔ WT1
➔ NEM1

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7
Q

Factores de reparación del ADN

A

➔ BRCA 1 y 2 (doble cadena)
➔ XPA (NER - una cadena)
➔ MSH2, MLH1, MSH6 (MMR - una ca)

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Pato Genes (10 decks)

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