Genetic Disorders Flashcards
1
Q
What percentage of DNA do you share with siblings?
A
50% and 25% if half siblings
2
Q
What percentage of DNA do you share with parents?
A
50%
3
Q
What percentage of DNA do you share with grandparents?
A
25%
4
Q
What percentage of DNA do you share with aunts and uncles?
A
25%
5
Q
What percentage of DNA do you share with 1st degree coins?
A
12.5%
6
Q
What is consanguineous mating?
A
Considered this if 2nd cousins or closers 3.13 shared DNA
7
Q
What happens the rarer the original allele?
A
The risk increase for contagious relationship
8
Q
Why draw a pedigree?
A
- Provides a clear simple summary of information
- Able to spot patterns easily
- Explain pattern to patient
- Calculate risk of passing on disease or being a carrier
- Allows informed choice
