GENETICS

Question 1

1943

Answer 1

Loutit and Mollison of England introduced the formula for the preservative acid-citrate-dextrose (ACD).

Question 2

In 1915, he determined the minimum amount of citrate needed for anticoagulation.

Answer 2

Lewisohn

Question 3

vein-to-vein transfusion of blood

Answer 3

Edward Lindemann

Question 4

James Blundell

Answer 4

first successful human transfusion, year 1892

Question 5

Pioneer of Blood banking techniques

Answer 5

Dr. Charles Drew

Question 6

1869

Answer 6

Braxton Hicks recommended sodium phosphate as a nontoxic anticoagulant

Question 7

Discovered the ABO blood groups

Answer 7

KARL LANDSTEINER 1901

Question 8

Rous and Turner

Answer 8

introduced a citrate-dextrose solution for the preservation of blood

Question 9

Structures that carry genetic information encoded on double-stranded DNA

Answer 9

CHROMOSOMES

Question 10

Humans have _____________ pairs of autosomes and _____________ set of sex chromosomes,

Answer 10

22 Pairs : 1 pair

Question 11

Generative cell cycle

Answer 11

G0 Gap - no division, resting phase
G1 - RNA & protein production
S (synthesis) - DNA replication
G2 - RNA & protein continuation
M (mitosis) - cell division

Question 12

what does N represents in cell division?

Answer 12

N - represent a single set of chromosome

Question 13

what is Gene?

Answer 13

smallest unit of inheritance

Question 14

Genetic locus

Answer 14

Site on chromosome where specific genes are located

Question 15

Inherited genes; actual genetic makeup

Answer 15

genotype

Question 16

Alleles

Answer 16

Alternative forms of a gene

Question 17

Opposite form of a gene, different allele

Answer 17

ANTITHETICAL

Question 18

Polymorphic

Answer 18

Having two or more possible alleles at a locus

Question 19

Physical, observable expression of inherited traits; detectable products

Answer 19

phenotype

Question 20

Pedigree chart:

Answer 20

Visual map that displays a family history and can display inheritance patterns for individual traits

Question 21

Equal expression of both alleles in phenotype

Answer 21

Codominant

Question 22

is carried
by either parent or both parents but is not generally seen the phenotypic level unless both parents carry the trait

Answer 22

recessive

Question 23

Only one allele must be inherited for it to be expressed; gene product always present

Answer 23

dominant

Question 24

Genes expressed with equal frequency in males and females, on non-sex chromosome

Answer 24

autosomal

Question 25

TRUE OR FALSE: Traits are exhibited most commonly in males

Answer 25

TRUE

Question 26

Mendelian Inheritance Principles

Answer 26

Law of Independent Segregation Law of Independent Assortment Inheritance patterns: PUNNETT SQUARE

Question 27

This states that traits inherited from different chromosomes expressed separately and discretely.

Answer 27

Law of Independent Assortment

Question 28

These are useful for understanding inheritance of blood groups and ramifications of heterozygosity or homozygosity.

Answer 28

Punnett Squares

Question 29

Law of Independent Segregation

Answer 29

Two members of a single gene pair passed from one generation to the next in SEPARATE gametes

Question 30

TRUE OR FALSE Agglutination reactions are generally weaker for homozygous cells and slightly stronger for heterozygous cells

Answer 30

FALSE Agglutination reactions are generally STRONGER for homozygous cells and slightly WEAKER for heterozygous cells

Question 31

CIS is?

Answer 31

Genes inherited on the same chromosome

Question 32

Trans is?

Answer 32

genes inherited on SEPARATE chromosomes. This can weaken the trait's expression.

Question 33

Fill in the blanks: _____________/secondary/second order occurs when a genetic marker is _____________ in the child but should have been transmitted by the alleged father

Answer 33

Indirect: absent