Genetics 2 Flashcards
(4 cards)
What is a pedigree?
It is a diagram of a family tree, of affected and unaffected individuals.
What is the testcross used for?
It is to determine the unknown genotype of the person with a dominant phenotype. Basically you have to find out whether the individual is homozygous dominant or heterozygous for the trait.
Tips for autosomal recessive pedigrees:
- homozygous recessive individual are affected
- heterozygous are carriers
- homozygous dominant is not affected
- normal parents can have affected offspring
- the condition can often appear suddenly or skip a generation
Tips for autosomal dominant pedigree:
- homozygous recessive individuals are not affected
- homozygous dominant and heterozygous is affected
- affected offspring have at least one affected parent
- the condition does not skip a generation