Genitourinary and Reproductive

Question 1

What place do loop diuretics work on?

Answer 1

Ascending loop

e.g. furosemide

Question 2

What place do thiazides act on?

Answer 2

DCT

e.g. Bendroflumethiazide

Question 3

What place do K+ sparing diuretics work on?

Answer 3

Collecting Ducts

e.g. spironolactone

Question 4

What 3 things can renal stones be made out of?

Answer 4

Calcium oxalate
Uric acid
Struvite

Question 5

What do you give to a patient with renal colic?

Answer 5

Tamsulosin

Nifedipine

Question 6

Causes of AKI. Give 3

Answer 6

Hypotension
Renal Stones
Malignancy

Question 7

Give 3 examples of nephrotoxic drugs:

Answer 7

NSAIDs
ACE inhibitors
Aminoglycosides

Question 8

What two medications do I give to CKD

Answer 8

ACE inhibitor

Statin

Question 9

Nephritic syndrome what are its characteristics?

Answer 9

Haematuria 
Proteinuria 
Hypertension 
Low urine volume 
E.g. Post Strep Glomerulonephritis, Goodpasteurs and lgA nephropathy.

Question 10

Give an example of 2nd line therapy for BPH.

Answer 10

5 alpha reductsase inhibitor: finasteride.

Question 11

How Is prostate cancer treated?

Answer 11

Localised: active surveillance
Radical Prostatectomy
Hormone therapy: goserelin!

Question 12

How do you treat renal cancer?

Answer 12

Radical nephrectomy

+ biological treatment such as sorafenib