Geriatrics Flashcards

(48 cards)

1
Q

How does minute ventilation change in the elderly?

A

Increases (increased dead space > increased minute vent to maintain CO2)

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2
Q

How does lung compliance change in the elderly?

A

Increase (think COPD esque) ~ easier to inflate the lungs

Increase in a given volume for a given pressure

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3
Q

How does lung elasticity change in the elderly?

A

Decreases.
Elastic recoil is lost ~ this promotes small airway collapse.
>increased dead space
>Decrease alveolar surface area
>V/Q mismatch
> increased A-a gradient!
> reduced PaO2

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4
Q

How is chest wall compliance changed with age?

A

Decreased chest wall compliance.
Chest wall is stiffer and less tendency to expand.
>calcification of joints
>diaphragmatic flattening
>A:P diameter
>decreased intervertebral disc height.
>decreased muscle strength

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5
Q

How does old age alter the response to hypercarbia and hypoxia?

A

Chemoreceptors are less sensitive
> risk of Hypoventilation
>risk of apnea
> risk of resp failure

***consider bipap and cpap

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6
Q

How does old age affect protective airway reflexes?

A

Reduced efficacy of cough and swallowing.
> increased risk of aspiration

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7
Q

How does old age affect airway tone?

A

Decreased muscle strength
> risk of resp failure
> risk of upper airway obstruction

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8
Q

What lung components are INCREASED in old age?

A

FRC
Residual volume
Closing capacity

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9
Q

What lung components are decreased in old age?

A

Viral capacity
Inspiratory reserve volume
Expiratory reserve volume
FEV & FEV1

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10
Q

At what age does closing capacity surpass FRC in the supine position?

A

~ 45 years

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11
Q

At what age does closing capacity surpass FRC in the standing position?

A

~65

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12
Q

How does old age affect TLC?

A

Not much
* increase in Residual volume reduces viral capacity

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13
Q

What are the 4 most prevalent cardiac diseases in the elderly?

A

HTN
CHF
CAD
And MI

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14
Q

What are the best indicators of cardiac reserve?

A

Exercise tolerance and the ability to perform daily living activities

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15
Q

What is the most common cause of death for the elderly in the postoperative period?

A

MI

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16
Q

How does the arterial system change with age?

A

Loss of elastin and increased collagen
> ^SVR
> ^ pulse pressure
> ^ myocardial wall tension
> ^ LV thickness (concentric hypertrophy)

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17
Q

How does the venous system change with age?

A

Decreased
Loss of elastin and increased collagen
>capacitance fx is diminished
Changes in blood volume cause HUGE changes in pressure

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18
Q

How does myocardial compliance change with age?

A

Decreased
Impaired relaxation > diastolic dysfunction
>greater pressure to fill
>filling pressure > volume
> ^HR reduces filling time

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19
Q

What is so important in a non-compliant ventricle?

A

Atrial kick

**increased pressure in that atria can cause Afib (leads to a lack of priming)

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20
Q

How is myocardial hypertrophy?

A

Increased
Concentric hypertrophy (reduces compliance and impairs relaxation)

21
Q

How does cardiac conduction change with age?

A

Decreased
Fibrosis of the conduction system

***loss of SA node tissue

(Increased likelihood of dysrhythmias)

22
Q

What is Virchow’s triad?

A

Venous stasis
Hypercoagulability
Endothelial dysfunction

23
Q

What is PRESERVED in the geriatric heart?

A

Systolic function

24
Q

What is increased in the geriatric heart?

A

SVR
pulse pressure
Prolonged circulation time

25
What is reduced in the geriatric heart?
Diastolic fx Stroke volume HR Decreased responsiveness to catecholamines Decreased CO
26
How is autonomic fx in the geriatric patient?
Decreased. >reduced baroreceptor activity > Syncope > greater Hemodynamic compromise following sympathectomy
27
How is the SNS tone affected in the geriatric patient?
Increased **higher NE concentration in the plasma BUT reduced sensitivity
28
How is PNS tone affect in the geriatric patient?
Decreased May limit anticholinergic ability
29
How does age affect the response to catecholamines?
Decreased > impairs receptor density > impaired B-receptor and adenylate cyclase coupling > reduced ability to increase HR during hypotension/stress
30
How much does MAC decrease for each decade of life after 40?
6%
31
How much should the dose of IV agent he reduced for the geriatric patient?
30-40%
32
How does aging affect the neutransmitter activity of the brain?
Reduced activity of Ach, NE, DA, and GABA
33
How is brain mass affect in the geriatric patient?
Reduced! ~ but does not affect mental capacity **Gray matter atrophies faster than white.
34
How does aging affect the peripheral nerves?
Decreased myelinated nerves
35
What is the most common CNS complication for the elderly?
Postoperative delirium
36
What are the traits of postoperative delirium?
Onset: early post-op period Presentation: easy to identify (disordered behavior, perception, memory) Risk factors: > D: drugs > E: electrolyte imbalance > L: lack of drugs (withdrawal) > I: infection > R: reduced sensory input > I: intracranial dysfunction > U: urinary retention/fecal impaction > M: myocardial event Tx: treat underlying cause, antipsychotics, and minimize poly pharmacy
37
What are the traits of postoperative cognitive dysfunction?
Onset: weeks to months after surgery Presentation: difficult to pinpoint (impaired concentration/ comprehension) Risk factors: > advanced age > cardiac surgery > long duration of surgery > high asa status > low education Tx: no specific tx
38
How does the elderly patient response to neuraxial anesthesia?
> Increased sensitivity of nerve tissue to local anesthetics (decreased number of myelinated nerves, diameter and conduction velocity) > increased sensitivity to intrathecal anesthetics ~ reduced CSF > increased sensitivity to epidural anesthetics ~ reduced epidural space > increased difficultly placing blocks **reduced response to epi test dose (greater risk of false negative response)
39
What factor remains the unchanged in the geriatric patient?
Serum creatinine
40
How does aging affect the kidney?
> Decreased renal blood flow > Decreased renal mass ~decrease glomeruli > Decreased creatinine clearance ~ reduced as a function of renal blood flow > GFR ~ decreases by 1 mL/min/year > decrease response to acid load > decreased aldosterone (inability to conserve sodium - risk of dehydration > decreased antidiuretic hormone response
41
Which protein production is increasing in a geriatric patient?
Alpha-1 acid glycoprotein
42
How does aging affect the liver?
> decreased hepatic mass > decreased hepatic blood flow > decreased perioperative hepatic function > decreased albumin production > decreased pseudocholinesterase production > decreased phase 1 reactions (phase 2 stay the same!) > decreased first pass metabolism
43
How does aging affect drug circulation?
Slower IV induction Faster inhalation induction
44
How does aging adjust surface area to body mass ratio?
Increased d/t Reduced lean body mass
45
How does aging affect the total body fat?
Increased ~ increased Vd of lipophilic drugs
46
How does aging affect lean body mass?
Decreased Less muscle causes: > Decreased nasal metabolic rate > Decreased total body water > Decreased blood volume > Decreased plasma volume > decreased plasma binding (increased free fraction~ albumin; decreased free fraction of basic drugs ~ 1-acid glycoproteins) > decrease rate of recovery from volatile anesthetics
47
What should the anesthetic provider anticipate for hydrophilic drugs in the geriatric population ?
Smaller Vd ~ higher than expected plasma concentration for a given dose
48
What is the most sensitive indicator of renal function and drug clearance
Creatinine clearance