GFR and filtration Flashcards
What is the path of blood from the aorta to the kidney>
Renal artery –> segmental artery –> interlobar artery –> arcuate artery –> interlobULAR artery –> afferent arteriole
Which type of nephron has a longer loop of Henle? Cortical or juxtamedullary?
Juxtamedullary
Which type of nephron would you find the vasa recta?
Juxtamedullary
True or false: The cortical nephron has a rich sympathetic nerve innervation?
True (the juxtamedullary has a poor sympathetic nerve innervation)
True or false: There is a small concentration of renin in the cortical nephron?
False. There is a high concentration of renin in the cortical nephron. (there is almost no renin in the juxtamedullary nephron)
How much blood is usually filtered in the glomerulus at any one time?
A. 50%
B. 40%
C. 20%
C. 20%. And always the same despite two types of nephron
What do the pedicels on the podocyte cause there to be?
Fenestration slits
What are the 3 layers of the filtration barrier?
- capillary endothelium
- basement membrane
- podocyte layer
What type of force is involved in filtering plasma to form ultrafiltrate?
Physical forces
What 3 forces control plasma filtration?
- Hydrostatic pressure in the capillary
- Hydrostatic pressure in the Bowman’s capsule
- Oncotic pressure difference
if pressure in the smooth muscle increases would it characteristically contract or relax?
contract
True or false: Myogenic responses tend to occur in the afferent arteriole?
True
What are the physiological limits of autoregulation?
80-180mmHG
What do the macula densa cells detect?
Chloride
Does the TGF (tubular glomerular feedback) response act as a long term or short term method of GFR regulation?
Short term
e.g. sitting to standing, coughing
