GI Flashcards
(23 cards)
what group has vast endotoxin production including alpha hemolysis
E.coli
what is the shiga like toxin
Found in both E.coli and shiggela, is a AB endotxin which is relased upon cell lysis.
ETEC give the location, type of Diarrhea and some general epi. Toxins?
Active site is the small intestine and secretory diarrhea. Travellers diarrhea. heat Labile and heat stable enterotoxins
EIEC give the location, type of Diarrhea and some general epi. Toxins?
active site is large intestine, Dysentrery, younger children in developing contrys, fever and cramps are associated due to the tissue invasion which is possible due to polymerization of cells which meidates movement cell to cell.
EPEC give the location, type of Diarrhea and some general epi. Toxins?
small intestine, secretory diarrhea, charateristic of childhood diarrrhea, no toxins uses sectroy proteins to cause deformation of cytoskeleton which causes is secretory diarrhea.
EHEC give the location, type of Diarrhea and some general epi. Toxins?
large intestine, diarrhea is caused by infamation rather then tissue invasion thus diarrhea is hemarogic coloitis. yes produces verodoxin which causes inflamation leading to adbominal pain. sources are either person to person but mostly transmitted through contaminated food.
EAEC give the location, type of Diarrhea and some general epi. Toxins?
Site of infection is small intestine, bloody watery diarrhea which may or may not have puss. STX toxin production. very long incubation period.
in which kind of infection would a relapse be expected or possible
Salmonella as it can enter a presiter state in the host macrophages
what is the main mech of disease for salmonella
inflammatory repones
which bacteria needs a larger enoculume to cause disease salmonella or shiggela
salmonella bc shigella needs as little at 100 organisms to cause disease
what is the causative agent for the plague
Yersinia persistis
what are the 2 forms of the pleague and what are there charateristics
bubonic- caused by a insect bite which infects lympatic system
Pnumonic- from human and infectes lungs through inhalation of air born infected droplets
is the cycle seen with yersinia persitis
- sylavatic and urban cycle which sees animals and insects remaining as a massive resivoir for the pleague and cycle the infection within there population which then may come into conctact with humans which then sees a cycle of humans creating insect carrier which then begin the cylavaitic cycle over again this is why it is so challanging to rid the world of the pleague
what is a key feature which allows necrosis in the pleague
yersinias ability to bind organic iron from heme in blood
how does S.aureus cause Disease in GI
intoxication via enterotoxin commonly enterotxin A which causes intesnse vomiting along with secrtory diarrhea
why is S.aureus so common in food related illness
BC high salt and sugar tolerance, also when heating kills bacteria but does not removed the heat stable enterotoxin
what are the 2 forms of disease cauased by bacillus cereus
- heat stable toxin form which causes vomiting and is associated w rice
- Heat labile form which is the darrheal form which is associated w meat or veggies
what is unquie about campylobacter
Microaerophilic conditions
- this bacteria causes frequent bloody stools which can last more then a week
epi- comes from farm related animals and infections in humans is from injestion of infected diseases
what is super unique about helipbacter
has a distinct helical shape
what is very charaterictic of Vibrio cholerare
Vibrio chloerare is know widly for 2 things first of which being its ability to produce the cholera toxin which is secreted in huge quanities which in turn causes disease. The disease it self is also known for causeing huge secrtory diarrhea. (active site is small intestine)
how does helopbacter avoid stomach acids
- production of urase which increase local pH
