GI Flashcards
(63 cards)
B12 deficiency can be caused by what type of anemia?
Pernicious anemia: autoimmune destruction/loss of gastric parietal cells that secrete intrinsic factor
A patient is complaining of “walking funny”, memory loss, and paresthesias. He also says he has not eaten anything in a few days but is having diarrhea. Lab results reveal macrocytosis (increased MCV) with hypersegmented neutrophils. What is the most common cause?
B12 deficiency
A patient is complaining of “walking funny”, memory loss, and paresthesias. He also says he has not eaten anything in a few days but is having diarrhea. Lab results reveal macrocytosis (increased MCV) with hypersegmented neutrophils. What is the best treatment for this patient?
IM or Oral B12
IM for pernicious anemia*
A patient is complaining of excessive vomiting and has voluminous, watery diarrhea. He denies any blood in his stool. Patient states he ate an egg salad made with mayonnaise; then had a milkshake for dessert. Labs reveal no fecal WBCs. What is the most likely cause of his condition?
S. aureus
- self-limiting
What is the most common cause of gastroenteritis for adults in North America?
Norovirus
What is the most common cause of diarrhea in children?
Rotavirus
A patient is complaining of excessive vomiting and has voluminous, watery diarrhea. He denies any blood in his stool. Patient states he ate fried rice at a Chinese restaurant. Labs reveal no fecal WBCs. What is the most likely cause of his condition?
Bacillus cereus
- self-limiting
A patient is complaining of excessive vomiting and has voluminous, “rice-water” diarrhea. She says she was in Lousiana and ate raw shellfish. What is the most common cause of this condition? How will you manage this patient?
Vibrio parahemolyticus = raw shellfish***
Vibrio cholera = overcrowded places
Fluid replacement is mainstay of tx
Abx = tetracyclines or fluoroquinolones
V. vulnificus diarrhea is associated with what?
Bacteremia and cellulitis
What is the most common cause of “travelers diarrhea”?
How do you manage this patient?
Enterotoxigenic E. coli
- Fluids
- If severe = fluoroquinolones
A patient is complaining of high fever, and RLQ pain with excessive vomiting and has small volumes of diarrhea. Pt says it started off with no blood then this morning it turned into bloody diarrhea. The patient states he ate what may have looked like undercooked chicken. Labs reveal fecal WBCs. Micro results reveal an “S-shaped; seagull shaped” organism. What is the most likely cause of his condition? And how do you manage it?
C. jejuni
-Erythromycin is 1st line*
What is the most common cause of bacterial enteritis in the US?
C. jejuni
MC antecedent event in Post-infectious Guillain-barre syndrome
A young patient is complaining of explosive, watery diarrhea. The patient is febrile and suddenly experiencing a seizure. WBC are >50K; a “leukmoid reaction.” Sigmoidoscoy reveals punctate areas of ulceration. What is the most common cause? And how do you manage it?
Shigella
- Fluids
- Bactrim is 1st line*
A patient is complaining of abdominal cramping, fever, vomiting, and mucusy-bloody diarrhea. The patient is a 9-year old boy, who upon questioning, reveals he licked his pet turtle on a dare. What is the most common cause of this condition and how will you manage it?
Salmonella gastroenteritis: S. typhirmurium
Fluids
If severe: Fluoroquinolone
“Pea soup stools” is associated with which diarrhea?
Salmonella typhi–typhoid fever
“rose spots” appear in 2nd week AFTER Cephalic phase
What 2 invasive infectious diarrheas mimic appendicitis?
- C. jejuni
2. yersinia Enerocolitica
A patient is complaining of watery diarrhea that has now progressed into bloody diarrhea. Patient has a low fever and is vomiting with crampy abdominal pain. What is the most common cause of this condition and how did this person become infected?
- Enerohemorrhagic E. coli (0157:H7)
- undercooked ground beef
unpasteurized milk/apple cider
daycare centers
contaminated water
A patient is complaining of watery diarrhea that has now progressed into bloody diarrhea. Patient has a low fever and is vomiting with crampy abdominal pain. Microbiolgy reveals E. coli (0157:H7). Why is abx tx controversial for children?
Increased incidence of Hemolytic Uremic Syndrome (HUS)
-Fluid replacement and supportive measures
What is the cause for “backpackers diarrhea”?
Giardia lamblia
What is the tx for Backpacker’s diarrhea?
Guardia lambda; METRONIDAZOLE
What is the tx of amebiasis?
Metronidazole
FURAZOLIDONE in children***
Which organism is most commonly seen in travelers to developing nations?
Amebiasis : Entamoeba histolytica
*causes liver abscesses
Which organism commonly causes chronic diarrhea with AIDS pts?
Cryptosporidium
*No proven tx–HAART
Which organism commonly causes diarrhea with homosexual men and pts with AIDS?
Isospora bella
*Tx with Bactrim